ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2013
Sleep endoscopy with midazolam: sedation level evaluation with bispectral analysis.
Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Society of Anesthesia and Sleep Medicine Guideline on Intraoperative Management of Adult Patients With Obstructive Sleep Apnea.Anesthesia and analgesia · 2018Guideline
- Drug-induced sedation endoscopy (DISE) classification systems: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2017Pooled it
- European position paper on drug-induced sedation endoscopy (DISE).Sleep & breathing = Schlaf & Atmung · 2014Guideline
- Reliability of drug-induced sedation endoscopy: interobserver agreement.Sleep & breathing = Schlaf & Atmung · 2017Trial
- Current Concepts of the Applications and Treatment Implications of Drug-Induced Sleep Endoscopy for the Management of Obstructive Sleep Apnoea.Diagnostics (Basel, Switzerland) · 2025Review
- The influence of different application patterns of propofol on the sedation courses during drug-induced sleep endoscopy.Laryngoscope investigative otolaryngology · 2024Article
- Effect of remimazolam on postoperative sleep quality in patients undergoing laparoscopic hysterectomy: A randomized controlled trial.Journal of anesthesia and translational medicine · 2024Article
- Modifications in Upper Airway Collapsibility during Sleep Endoscopy with a Mandibular Positioner: Study in Snorers and Obstructive Sleep Apnea Patients.Journal of clinical medicine · 2024Article
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Myoelectric characteristics of tensor palatini and collapsibility of upper airway in OSA patients with different phenotypes under DISE.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Depth of sedation during drug induced sedation endoscopy monitored by BiSpectral Index® and Cerebral State Index®.Sleep & breathing = Schlaf & Atmung · 2021Article
- Comparison of upper airway obstruction during zolpidem-induced sleep and propofol-induced sleep in patients with obstructive sleep apnea: a pilot study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Can be compared obstructive respiratory events during drug induced sleep endoscopy (DISE) and nocturnal polysomnography.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- The Effect of the Modified Jaw-Thrust Maneuver on the Depth of Sedation During Drug-Induced Sleep Endoscopy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Drug induced sleep endoscopy: its role in evaluation of the upper airway obstruction and patient selection for surgical and non-surgical treatment.Journal of thoracic disease · 2018Review
- Drug-Induced Sedation Endoscopy (DISE) DATA FUSION system: clinical feasibility study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Article
- Drug-induced sedation endoscopy: data capture, data analysis and sedation administration.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Article
- Review
- When continuous positive airway pressure (CPAP) fails.Journal of thoracic disease · 2016Review
- Depth-dependent changes of obstruction patterns under increasing sedation during drug-induced sedation endoscopy: results of a German monocentric clinical trial.Sleep & breathing = Schlaf & Atmung · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study examines subjects' level of consciousness with bispectral analysis in sedation endoscopy of the upper airway. STUDY
designA prospective study.
settingUniversity hospital. SUBJECTS AND
methodsBispectral analysis levels recorded in natural sleep of 43 patients with obstructive sleep apnea during an overnight polysomnographic sleep study were directly compared with the levels recorded during midazolam sedation sleep endoscopy in the same subjects. The possible muscle relaxation effect of midazolam was examined via surface chin electrodes. Supine Müller maneuver findings in 50 patients with obstructive sleep apnea were also compared with soft tissue dynamics during midazolam sedation sleep endoscopy.
resultsIn our study of the 43 patients with bispectral analysis during natural sleep and midazolam sedation sleep endoscopy, a predominance of bispectral analysis values indicating N1 and N2 sleep was observed during the sedation study. Midazolam failed to achieve deeper levels of sleep with minimal N3 and no convincing rapid eye movement. As N1 and N2 are the stages during which maximal dynamic activities occur, and they make up an average of 70.5% of total sleep time, from 210 sleep studies at our laboratory, the present technique would be ideal as a surgical assessment tool. No muscle relaxation effect could be detected at our protocol dose of midazolam. The supine Müller maneuver findings were significantly different from those observed during sedation sleep.
conclusionThese findings support the value of sleep endoscopy as an efficient and informative technique for the examination of upper airway dynamics relevant to focused surgical planning.
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