Evidence map›Paper›PMID 23111819›Full record

Trial reportEuropean radiology2013

Complications and clinical outcome of hepatic artery embolisation in patients with hereditary haemorrhagic telangiectasia.

Ajay Chavan, Lars Luthe, Michael Gebel, Hannelore Barg-Hock, Hans Seifert, Rudolph Raab, Timm Kirchhoff, B Schmuck

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Cardiac and Hemodynamic Manifestations of Hereditary Hemorrhagic Telangiectasia.The International journal of angiology : official publication of the International College of Angiology, Inc · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Preoperative arterial embolization of large liver hemangiomas.Diagnostic and interventional radiology (Ankara, Turkey)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ajay ChavanDepartment of Diagnostic and Interventional Radiology, Klinikum Oldenburg, Rahel Straus Strasse 10, 26133 Oldenburg, Germany. chavan.ajay@klinikum-oldenburg.de
Lars Luthe
Michael Gebel
Hannelore Barg-Hock
Hans Seifert
Rudolph Raab
Timm Kirchhoff
B Schmuck
Klinikum Oldenburg · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatic artery embolisation (HAE) in patients with hereditary haemorrhagic telangiectasia (HHT) is controversial because of the associated complications and unproven long-term benefit. We present our results in 20 such patients over a time span of 17 years.

methodsStaged HAE was performed using polyvinyl alcohol (PVA) particles and coils. Complications, clinical symptoms and cardiac output were assessed before and after therapy as well as at the end of follow-up (median 92 months, range 26-208 months).

resultsTwo patients died within 30 days following HAE (10 %). Four further deaths resulted from causes unrelated to HAE. Ischaemic cholangitis, cholecystitis and focal hepatic necrosis with biliary sepsis necessitated re-intervention in four patients. In all but one patient, clinical symptoms resolved with mean cardiac output falling from 11.84 ± 3.22 l/min pre-treatment to 8.13 ± 2.67 l/min at the end of follow-up (P < 0.001). One patient required liver transplantation for de novo symptoms of portal hypertension 4 years after primary symptoms had been cured by HAE.

conclusionThe 30-day mortality of HAE in patients with HHT is 10 %. The rate of complications requiring re-intervention is 20 %. Clinical response at long-term follow-up is satisfactory.

Indexed as

Hepatic ArteryAdultAgedBiliary Tract DiseasesEmbolization, TherapeuticFemaleHumansLongitudinal StudiesMaleMiddle AgedPolyvinyl AlcoholTelangiectasia, Hereditary HemorrhagicTreatment OutcomePolyvinyl Alcohol

Identifiers

PMID23111819
PMCPMC3599206
OpenAlexW2073503127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.