Evidence map›Paper›PMID 23111739›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2012

Increased dispersion of ventricular repolarization in Emery Dreifuss muscular dystrophy patients.

Vincenzo Russo, Anna Rago, Luisa Politano, Andrea Antonio Papa, Federica Di Meo, Maria Giovanna Russo, Paolo Golino, Raffaele Calabrò, Gerardo Nigro

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. The effect of atrial preference pacing on atrial fibrillation electrophysiological substrate in Myotonic Dystrophy type 1 population.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2014
    Trial
  2. Atrial fibrillation burden in Myotonic Dystrophy type 1 patients implanted with dual chamber pacemaker: the efficacy of the overdrive atrial algorithm at 2 year follow-up.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2013
    Trial
  3. Role of cardiovascular magnetic resonance in diagnosis and management of muscular dystrophies.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Review
  4. Role ofBiomolecules · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Arrhythmic risk evaluation in myotonic dystrophy: the importance of selection criteria and methodological approach.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2017
    Article
  11. The role of the atrial electromechanical delay in predicting atrial fibrillation in beta-thalassemia major patients.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2017
    Article
  12. Increased heterogeneity of ventricular repolarization in myotonic dystrophy type 1 population.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2016
    Article
  13. Electrocardiographic Presentation, Cardiac Arrhythmias, and Their Management in β-Thalassemia Major Patients.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2016
    Review
  14. Novel mutations in LMNA A/C gene and associated phenotypes.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2015
    Article
  15. Ventricular fibrillation induced by coagulating mode bipolar electrocautery during pacemaker implantation in Myotonic Dystrophy type 1 patient.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2014
    Article
  16. Adenosine-induced sinus tachycardia in a patient with Myotonic Dystrophy type 1.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2014
    Article
  17. Far field R-wave sensing in Myotonic Dystrophy type 1: right atrial appendage versus Bachmann's bundle region lead placement.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2014
    Article
  18. Article
  19. Article
  20. Advances in basic and clinical research in laminopathies.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Vincenzo RussoChair of Cardiology, 2nd University of Naples, Naples, Italy.
Anna Rago
Luisa Politano
Andrea Antonio Papa
Federica Di Meo
Maria Giovanna Russo
Paolo Golino
Raffaele Calabrò
Gerardo Nigro
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSudden cardiac death (SCD) is common in patients with Emery-Dreifuss muscular dystrophy (EDMD) and is attributed to the development of life-threatening arrhythmias that occur in the presence of normal left ventricular systolic function. Heterogeneity of ventricular repolarization is considered to provide an electrophysiological substrate for malignant arrhythmias. QTc dispersion (QTc-D) and JTc dispersion (JTc-D) are electrocardiographic parameters indicative of heterogeneity of ventricular repolarization. The aim of our study was to evaluate the heterogeneity of ventricular repolarization in patients with Emery-Dreifuss muscular dystrophy with preserved systolic and diastolic cardiac function. MATERIAL/

methodsThe study involved 36 EDMD patients (age 20 ± 12, 26 M) and 36 healthy subjects used as controls, matched for age and sex. Heart rate, QRS duration, maximum and minimum QT and JT interval, QTc-D and JTc-D measurements were performed.

resultsCompared to the healthy control group, the EDMD group presented increased values of QTc-D (82.7 ± 44.2 vs. 53.1 ± 13.7; P=0,003) and JTc-D (73.6 ± 32.3 vs. 60.4 ± 11.1 ms; P=0.001). No correlation between QTc dispersion and ejection fraction (R=0.2, P=0.3) was found.

conclusionsOur study showed a significant increase of QTc-D and JTc-D in Emery-Dreifuss muscular dystrophy patients with preserved systolic and diastolic cardiac function.

Indexed as

Case-Control StudiesElectrocardiographyFemaleHeart VentriclesHumansMaleMuscular Dystrophy, Emery-DreifussUltrasonographyVentricular FunctionYoung Adult

Identifiers

PMID23111739
PMCPMC3560603
OpenAlexW2161932638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.