Evidence map›Paper›PMID 23111700›Full record

ReviewSeminars in immunopathology2013

Helicobacter pylori infection and gastric carcinogenesis in rodent models.

Tetsuya Tsukamoto, Takeshi Toyoda, Tsutomu Mizoshita, Masae Tatematsu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Infection and immunity · 2025
    Article
  2. Article
  3. Review
  4. Vitamin D3 InhibitsFrontiers in cellular and infection microbiology · 2020
    Article
  5. The prevalence ofGut pathogens · 2018
    Article
  6. Prevention of Gastric Cancer: Eradication of Helicobacter Pylori and Beyond.International journal of molecular sciences · 2017
    Review
  7. Review
  8. Helicobacter pylori as an oncogenic pathogen, revisited.Expert reviews in molecular medicine · 2017
    Review
  9. The Clinical Evidence LinkingCellular and molecular gastroenterology and hepatology · 2017
    Review
  10. Review
  11. Article
  12. Article
  13. Role of Helicobacter pylori in Gastric Neoplasia.Current infectious disease reports · 2014
    Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tetsuya TsukamotoDepartment of Diagnostic Pathology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan. ttsukamt@fujita-hu.ac.jp
Takeshi Toyoda
Tsutomu Mizoshita
Masae Tatematsu
Fujita Health University Hospital · JPNagoya City University · JPNational Institute of Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori infection is an important factor for gastric carcinogenesis in human. In carcinogen-treated Mongolian gerbils, H. pylori infection enhances stomach carcinogenesis, while infection alone induced severe hyperplasia called heterotopic proliferative glands. A high-salt diet or early acquisition of the bacteria exacerbates inflammation and carcinogenesis. Oxygen radical scavengers or anti-inflammatory chemicals as well as eradication of H. pylori are effective to prevent carcinogenesis. H. pylori-associated inflammation induces intestinal metaplasia and intestinalization of stomach cancers independently. It is necessary to control cancer development not only in H. pylori-positive cases but also in H. pylori-negative metaplastic gastritis.

Indexed as

Stomach NeoplasmsAnimalsAnti-Inflammatory AgentsFree Radical ScavengersGerbillinaeHelicobacter InfectionsHelicobacter pyloriHumansMetaplasiaMiceNeoplasms, ExperimentalRatsAnti-Inflammatory AgentsFree Radical Scavengers

Identifiers

PMID23111700
OpenAlexW2064968444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.