Evidence map›Paper›PMID 23111650›Full record

ReviewJournal of investigative medicine : the official publication of the American Federation for Clinical Research2013

Insulin signaling and insulin resistance.

Elmus G Beale

Open access · greenAbstract readReview
In one paragraph

Review in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 113 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Insulin Resistance and Inflammation.International journal of molecular sciences · 2026
    Review
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  12. Alteration of the NJournal of ovarian research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Elmus G BealeDepartment of Medical Education, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA. elmus.beale@ttuhsc.edu
Texas Tech University · US

Funding

AFMR-Translational Medical Research Symposia SeriesR13RR023236 · NCRR · AMERICAN FEDERATION FOR MEDICAL RESEARCH · PI ZUCKER, DEBORAH R · 2006 to 2010
$263k
REGULATION OF TISSUE SPECIFIC GENE EXPRESSIONR01GM039895 · NIGMS · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI BEALE, ELMUS G · 1995 to 1997
–
NCRR NIH HHS R13 RR023236NIGMS NIH HHS R01 GM039895
6 · The paper itself

Abstract

Insulin resistance or its sequelae may be the common etiology of maladies associated with metabolic syndrome (eg, hypertension, type 2 diabetes, atherosclerosis, heart attack, stroke, and kidney failure). It is thus important to understand those factors that affect insulin sensitivity. This review stems from the surprising discovery that interference with angiotensin signaling improves insulin sensitivity, and it provides a general overview of insulin action and factors that control insulin sensitivity.

Indexed as

AnimalsCongresses as TopicDiabetes Mellitus, Type 2HumansHypertensionInsulinInsulin ResistanceMetabolic SyndromeSignal TransductionInsulin

Identifiers

PMID23111650
PMCPMC3640267
OpenAlexW88151426

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.