Evidence map›Paper›PMID 23111501›Full record

ArticlePlant molecular biology2013

Functional analysis of splice variant expression of MADS AFFECTING FLOWERING 2 of Arabidopsis thaliana.

Sarah Marie Rosloski, Anandita Singh, Sathya Sheela Jali, Sureshkumar Balasubramanian, Detlef Weigel, Vojislava Grbic

Open access · hybridAbstract read
In one paragraph

Article in Plant molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 85 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Identification and Alternative Splicing Profile of theInternational journal of molecular sciences · 2023
    Article
  6. meLife · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Polymerase II-Associated Factor 1 Complex-RegulatedFrontiers in plant science · 2022
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Beyond the Genetic Pathways, Flowering Regulation Complexity inInternational journal of molecular sciences · 2021
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Sarah Marie RosloskiDepartment of Biology, Western University, London, ON N6A 5B8, Canada.
Anandita Singh
Sathya Sheela Jali
Sureshkumar Balasubramanian
Detlef Weigel
Vojislava Grbic
Western University · CAAustralian Regenerative Medicine Institute · AUMax Planck Institute for Developmental Biology · DETERI University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The MADS-AFFECTING FLOWERING 2 (MAF2) gene of Arabidopsis thaliana has been characterized as a repressor of flowering. The molecular basis of MAF2 gene function and role of alternative MAF2 transcripts in flowering time modulation is not understood. MAF2 splice variant expression was quantified in cold-acclimated plants by quantitative RT-PCR. Cold influenced the abundance of splice variants and prompted a functional study of splice forms. Individual variants were overexpressed in the Col background and were assayed for their ability to delay flowering. Overexpression of MAF2 variants 2 and 4 had limited effect on flowering time. Overexpression of MAF2 splice variant 1 resulted in early flowering and affected the expression of the endogenous MAF2 gene and its paralogues, confounding functional assessment. In the Ll-2 Arabidopsis accession, a MAF2, MAF3, MAF4 and FLC null line, MAF2 var1 was consistent in its effect on reproductive delay under ambient and reduced temperatures, indicating that it acts as a repressor of flowering.

Indexed as

Alternative SplicingArabidopsisArabidopsis ProteinsCold TemperatureFlowersGene Expression Regulation, PlantGenes, PlantGenetic VariationMADS Domain ProteinsPlants, Genetically ModifiedTime FactorsArabidopsis ProteinsMADS Domain Proteins

Identifiers

PMID23111501
PMCPMC3527738
OpenAlexW1992956019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.