Evidence map›Paper›PMID 23111393›Full record

ArticleThe American journal of the medical sciences2013

Severe leprosy reactions due to Mycobacterium lepromatosis.

Xiang Y Han, Jose Jessurun

Open access · greenAbstract readCase Reports
In one paragraph

Article in The American journal of the medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. British Red Squirrels (Interdisciplinary perspectives on infectious diseases · 2026
    Article
  4. Article
  5. Unraveling Drug Resistance inInternational journal of microbiology · 2025
    Review
  6. Molecular and Serological Surveillance forAnimals : an open access journal from MDPI · 2024
    Article
  7. Article
  8. Lepromatous leprosy infection fromJAAD case reports · 2024
    Article
  9. Article
  10. Frontiers in microbiology · 2021
    Review
  11. Cutaneous Mycobacterial Infections.Clinical microbiology reviews · 2018
    Review
  12. Article
  13. Review
  14. "Lucio's Phenomenon" Associated with Mycobacterium lepromatosis.The American journal of tropical medicine and hygiene · 2016
    Article
  15. Article
  16. A Lepromatous Leprosy Patient with Permanent Disability.The American journal of tropical medicine and hygiene · 2015
    Article
  17. Article
  18. Article
  19. Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Xiang Y HanDepartment of Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. xhan@mdanderson.org
Jose Jessurun
The University of Texas MD Anderson Cancer Center · USUniversity of Minnesota · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Kathrin Milbury · 1985 to 2026
$290.8M
NCI NIH HHS CA16672NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

Leprosy is caused by the well-known Mycobacterium leprae and the newly discovered M lepromatosis. Here, the authors describe 2 cases of leprosy with unusual clinical presentation caused by M lepromatosis. The patients, a 32-year-old man and a 50-year-old woman, both of Mexican origin, manifested high fever, lymphadenopathy and florid skin lesions in the form of erythema nodosum and Lucio's phenomenon as the first clinical presentation. Heavy infiltration of acid-fast bacilli was identified in the tissues that led to the diagnosis of lepromatous leprosy or diffuse leprosy. The patients were treated with multidrug regimen and responded appropriately. From the lymph node tissue, the authors showed the bacillus to be M lepromatosis, not M leprae as presumed previously, by differential polymerase chain reactions and analysis of gene sequences. These cases add to the growing studies on this organism, expand its endemic regions in Mexico and provide more clinical insight.

Indexed as

MycobacteriumAdultFemaleHumansLeprosyMaleMiddle Aged

Identifiers

PMID23111393
PMCPMC3529828
OpenAlexW2056802032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.