Evidence map›Paper›PMID 23110994›Full record

ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2013

Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood.

Claire M A Haworth, Oliver S P Davis, Robert Plomin

Abstract readTwin Study
In one paragraph

Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
193citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

193 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Heritability of autism spectrum disorders: a meta-analysis of twin studies.Journal of child psychology and psychiatry, and allied disciplines · 2016
    Pooled it
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  7. CATSLife: A Study of Lifespan Behavioral Development and Cognitive Functioning.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019
    Trial
  8. Genetic specificity of face recognition.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Trial
  9. Trial
  10. Article
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  12. Childhood trauma and subclinical cin early adulthood: A genetically informative study.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  13. Article
  14. Harmonization of SDQ and ASEBA Phenotypes: Measurement Variance Across Cohorts.Journal of psychopathology and behavioral assessment · 2025
    Article
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133 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Claire M A HaworthInstitute of Psychiatry, King's College London, London, UK. Claire.Haworth@kcl.ac.uk
Oliver S P Davis
Robert Plomin

Funding

Genetics, School environments and cognitive developmentR01HD044454 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2005 to 2014
$3.4M
Genetics of Mathematical Cognition and DisabilitiesR01HD059215 · NICHD · OHIO STATE UNIVERSITY · PI PETRILL, STEPHEN A. · 2009 to 2012
$2.4M
GENETICS OF GENERAL AND SPECIFIC MATH DISABILITIESR01HD046167 · NICHD · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI PETRILL, STEPHEN A · 2003 to 2005
$1.6M
Reading disability QTLs: pooled DNA on microarraysR01HD049861 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2006 to 2008
$794k
European Research Council 295366Medical Research Council G0500079Medical Research Council G0500079(73692)Medical Research Council G0901245Medical Research Council G19/2Medical Research Council G19/2(78332)Medical Research Council G9424799NICHD NIH HHS HD044454NICHD NIH HHS HD046167NICHD NIH HHS HD049861NICHD NIH HHS HD059215NICHD NIH HHS R01 HD044454NICHD NIH HHS R01 HD046167NICHD NIH HHS R01 HD049861NICHD NIH HHS R01 HD059215Wellcome Trust 084728Wellcome Trust GR075492
6 · The paper itself

Abstract

The Twins Early Development Study (TEDS) is a large longitudinal sample of twins born in England and Wales between 1994 and 1996. The focus of TEDS has been on cognitive and behavioral development, including difficulties in the context of normal development. TEDS began when multiple births were identified from birth records and the families were invited to take part in the study; 16,810 pairs of twins were originally enrolled in TEDS. More than 10,000 of these twin pairs remain enrolled in the study to date. DNA has been collected for more than 7,000 pairs, and genome-wide genotyping data for two million DNA markers are available for 3,500 individuals. The TEDS families have taken part in studies when the twins were aged 2, 3, 4, 7, 8, 9, 10, 12, 14, and 16 years of age. Data collection is currently underway to assess the adult destinations of the twins as they move from school to university and the workplace. Between January 2012 and December 2014, all of the TEDS twins will turn 18, and the study will transition to an adult sample. TEDS represents an outstanding resource for investigating the developmental effects of genes and environments on complex quantitative traits from childhood to young adulthood and beyond.

Indexed as

Adolescent DevelopmentGenetics, BehavioralRegistriesAdolescentAdultChildChild Behavior DisordersChild, PreschoolCognition DisordersDiseases in TwinsFemaleHumansInfantInfant, NewbornLongitudinal StudiesMale

Identifiers

PMID23110994
PMCPMC3817931

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.