ArticleInternational archives of medicine2012
Sensitivity, specificity and predictive values of linear and nonlinear indices of heart rate variability in stable angina patients.
Article in International archives of medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Application of Heart Rate Variability in Diagnosis and Prognosis of Individuals with Diabetes Mellitus: Systematic Review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2016Pooled it
- Heart Rate Variability Features as Predictors of Intermittent Theta-Burst Stimulation Response in Posttraumatic Stress Disorder.Neuromodulation : journal of the International Neuromodulation Society · 2022Trial
- The effect of oxybutynin on cardiac autonomic modulation in healthy subjects.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2014Trial
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- Doppler signal analysis of the tricuspid valve in healthy fetuses during the first trimester: a cohort study.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Article
- Evaluation of Heart Rate Variability by Smartphone App Using Pulse Photoplethysmography in Acute Myocardial Infarction.Research in heart yield and translational medicine · 2025Article
- Article
- Cardioautonomic lability assessed by heart rate variability changes in Royal Canadian Mounted Police cadets during the cadet training program.Frontiers in psychology · 2023Article
- Do heart rate variability indices present potential to predict late postmenopausal? A retrospective study.Revista da Associacao Medica Brasileira (1992) · 2022Observational
- A Study of Cardiac Autonomic Functions in Patients with Chronic Stable Angina Undergoing Percutaneous Coronary Revascularization.Medeniyet medical journal · 2021Article
- Can short-term heart rate variability predict coronary artery disease in patients undergoing elective coronary angiography due to typical chest pain?Journal of clinical and translational research · 2020Article
- Article
- Effect of Percutaneous Coronary Intervention on Heart Rate Variability in Coronary Artery Disease Patients.European cardiology · 2018Review
- Sensitivity, Specificity and Predictive Value of Heart Rate Variability Indices in Type 1 Diabetes Mellitus.Arquivos brasileiros de cardiologia · 2017Article
- Complexity Change in Cardiovascular Disease.International journal of biological sciences · 2017Review
- Altered heart rate variability depend on the characteristics of coronary lesions in stable angina pectoris.Anatolian journal of cardiology · 2015Article
- Changes in Heart Rate Variability Parameters after Elective Percutaneous Coronary Intervention.The journal of Tehran Heart Center · 2015Article
- Cardiovascular autonomic function analysis using approximate entropy from 24-h heart rate variability and its frequency components in patients with type 2 diabetes.Journal of diabetes investigation · 2015Article
- A single bout of exercise with a flexible pole induces significant cardiac autonomic responses in healthy men.Clinics (Sao Paulo, Brazil) · 2014Article
- Vocal complaint in physical education teachers and its association with the cardiovascular system.International archives of medicine · 2014Article
Corrections and comments
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Authors and funding
12 authors.
Funding
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Abstract
unlabelled
backgroundDecreased heart rate variability (HRV) is related to higher morbidity and mortality. In this study we evaluated the linear and nonlinear indices of the HRV in stable angina patients submitted to coronary angiography.
methodsWe studied 77 unselected patients for elective coronary angiography, which were divided into two groups: coronary artery disease (CAD) and non-CAD groups. For analysis of HRV indices, HRV was recorded beat by beat with the volunteers in the supine position for 40 minutes. We analyzed the linear indices in the time (SDNN [standard deviation of normal to normal], NN50 [total number of adjacent RR intervals with a difference of duration greater than 50ms] and RMSSD [root-mean square of differences]) and frequency domains ultra-low frequency (ULF) ≤ 0,003 Hz, very low frequency (VLF) 0,003 - 0,04 Hz, low frequency (LF) (0.04-0.15 Hz), and high frequency (HF) (0.15-0.40 Hz) as well as the ratio between LF and HF components (LF/HF). In relation to the nonlinear indices we evaluated SD1, SD2, SD1/SD2, approximate entropy (-ApEn), α1, α2, Lyapunov Exponent, Hurst Exponent, autocorrelation and dimension correlation. The definition of the cutoff point of the variables for predictive tests was obtained by the Receiver Operating Characteristic curve (ROC). The area under the ROC curve was calculated by the extended trapezoidal rule, assuming as relevant areas under the curve ≥ 0.650.
resultsCoronary arterial disease patients presented reduced values of SDNN, RMSSD, NN50, HF, SD1, SD2 and -ApEn. HF ≤ 66 ms2, RMSSD ≤ 23.9 ms, ApEn ≤-0.296 and NN50 ≤ 16 presented the best discriminatory power for the presence of significant coronary obstruction.
conclusionWe suggest the use of Heart Rate Variability Analysis in linear and nonlinear domains, for prognostic purposes in patients with stable angina pectoris, in view of their overall impairment.
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