ArticleThe Plant cell2012
Conserved noncoding sequences highlight shared components of regulatory networks in dicotyledonous plants.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 76 citations in OpenAlex.
- Article
- Two deeply conserved non-coding sequences control PLETHORA1/2 expression and coordinate embryo and root development.Plant communications · 2025Article
- Genome-Wide Identification of DREB Gene Family in Kiwifruit and Functional Characterization of Exogenous 5-ALA-Mediated Cold Tolerance via ROS Scavenging and Hormonal Signaling.Plants (Basel, Switzerland) · 2025Article
- Comparative analysis of the GATA transcription factors in sevenFrontiers in plant science · 2025Article
- Genome-wide identification of kiwifruit KBMC plant biology · 2024Article
- Article
- Genome-wide comparative analysis of the valine glutamine motif containing genes in four Ipomoea species.BMC plant biology · 2023Article
- Identification of clade-wide putativeHorticulture research · 2023Article
- Genome-wide identification and characterization of NBS-encoding genes in the sweet potato wild ancestorOpen life sciences · 2022Article
- PlantRegMap: charting functional regulatory maps in plants.Nucleic acids research · 2020Article
- Enhanced Maps of Transcription Factor Binding Sites Improve Regulatory Networks Learned from Accessible Chromatin Data.Plant physiology · 2019Article
- Conserved noncoding sequences conserve biological networks and influence genome evolution.Heredity · 2018Article
- TF2Network: predicting transcription factor regulators and gene regulatory networks in Arabidopsis using publicly available binding site information.Nucleic acids research · 2018Article
- Bringing numerous methods for expression and promoter analysis to a public cloud computing service.Bioinformatics (Oxford, England) · 2018Article
- Genome-scale examination of NBS-encoding genes in blueberry.Scientific reports · 2018Article
- GC Content Heterogeneity Transition of Conserved Noncoding Sequences Occurred at the Emergence of Vertebrates.Genome biology and evolution · 2016Article
- A method for identification of highly conserved elements and evolutionary analysis of superphylum Alveolata.BMC bioinformatics · 2016Article
- A Collection of Conserved Noncoding Sequences to Study Gene Regulation in Flowering Plants.Plant physiology · 2016Article
- Purifying selection acts on coding and non-coding sequences of paralogous genes in Arabidopsis thaliana.BMC genomics · 2016Article
- Evolution of DNA-Binding Sites of a Floral Master Regulatory Transcription Factor.Molecular biology and evolution · 2016Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
Conserved noncoding sequences (CNSs) in DNA are reliable pointers to regulatory elements controlling gene expression. Using a comparative genomics approach with four dicotyledonous plant species (Arabidopsis thaliana, papaya [Carica papaya], poplar [Populus trichocarpa], and grape [Vitis vinifera]), we detected hundreds of CNSs upstream of Arabidopsis genes. Distinct positioning, length, and enrichment for transcription factor binding sites suggest these CNSs play a functional role in transcriptional regulation. The enrichment of transcription factors within the set of genes associated with CNS is consistent with the hypothesis that together they form part of a conserved transcriptional network whose function is to regulate other transcription factors and control development. We identified a set of promoters where regulatory mechanisms are likely to be shared between the model organism Arabidopsis and other dicots, providing areas of focus for further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.