ArticlePloS one2012
Smooth pursuit and visual occlusion: active inference and oculomotor control in schizophrenia.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
47 citing papers in PubMed, 93 citations in OpenAlex.
- Free energy, precision and learning: the role of cholinergic neuromodulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- Schizophrenia and disordered sensorimotor control: challenges, mechanisms and opportunities.Brain : a journal of neurology · 2026Review
- Schizophrenia recognition via eye movement features in video paradigm.European archives of psychiatry and clinical neuroscience · 2026Article
- Active Inference and Functional Parametrisation: Differential Flatness and Smooth Random Realisation.Entropy (Basel, Switzerland) · 2026Article
- The phantastic organ: predictive processing in the brain.Frontiers in psychology · 2026Review
- Contrasting predictive coding and representational accounts of perceptual organization, stimulus predictability, and attentional modulation in the visual cortical hierarchy.Neuroscience of consciousness · 2026Review
- Predictive interception across speed profiles.Frontiers in neural circuits · 2026Article
- Altered Effective Connectivity Within a Thalamocortical Corollary Discharge Network in Individuals With Schizophrenia.Schizophrenia bulletin · 2025Article
- The Many Roles of Precision in Action.Entropy (Basel, Switzerland) · 2024Review
- The Relationship Between Environmental Statistics and Predictive Gaze Behaviour During a Manual Interception Task: Eye Movements as Active Inference.Computational brain & behavior · 2024Article
- Individual prediction tendencies do not generalize across modalities.Psychophysiology · 2024Article
- Eye Movement Abnormalities Can Distinguish First-Episode Schizophrenia, Chronic Schizophrenia, and Prodromal Patients From Healthy Controls.Schizophrenia bulletin open · 2023Article
- Active inference, morphogenesis, and computational psychiatry.Frontiers in computational neuroscience · 2022Article
- Spatio-Temporally Efficient Coding Assigns Functions to Hierarchical Structures of the Visual System.Frontiers in computational neuroscience · 2022Article
- Gut inference: A computational modelling approach.Biological psychology · 2021Article
- Rational inattention and tonic dopamine.PLoS computational biology · 2021Article
- A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders.PLoS computational biology · 2020Article
- Voluntary control of auditory hallucinations: phenomenology to therapeutic implications.NPJ schizophrenia · 2020Review
- Tracking the Mind's Eye: Primate Gaze Behavior during Virtual Visuomotor Navigation Reflects Belief Dynamics.Neuron · 2020Article
- Humans adapt their anticipatory eye movements to the volatility of visual motion properties.PLoS computational biology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
This paper introduces a model of oculomotor control during the smooth pursuit of occluded visual targets. This model is based upon active inference, in which subjects try to minimise their (proprioceptive) prediction error based upon posterior beliefs about the hidden causes of their (exteroceptive) sensory input. Our model appeals to a single principle--the minimisation of variational free energy--to provide Bayes optimal solutions to the smooth pursuit problem. However, it tries to accommodate the cardinal features of smooth pursuit of partially occluded targets that have been observed empirically in normal subjects and schizophrenia. Specifically, we account for the ability of normal subjects to anticipate periodic target trajectories and emit pre-emptive smooth pursuit eye movements--prior to the emergence of a target from behind an occluder. Furthermore, we show that a single deficit in the postsynaptic gain of prediction error units (encoding the precision of posterior beliefs) can account for several features of smooth pursuit in schizophrenia: namely, a reduction in motor gain and anticipatory eye movements during visual occlusion, a paradoxical improvement in tracking unpredicted deviations from target trajectories and a failure to recognise and exploit regularities in the periodic motion of visual targets. This model will form the basis of subsequent (dynamic causal) models of empirical eye tracking measurements, which we hope to validate, using psychopharmacology and studies of schizophrenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.