ArticleKorean journal of pathology2012
Identifying Polymorphisms in IL-31 and Their Association with Susceptibility to Asthma.
Article in Korean journal of pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- IL-31: State of the Art for an Inflammation-Oriented Interleukin.International journal of molecular sciences · 2022Pooled it
- Biomarkers of type 2 and non-type 2 inflammation in asthma exacerbations.Central-European journal of immunology · 2024Article
- Interleukin-31 and soluble CD40L: new candidate serum biomarkers that predict therapeutic response in multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Review
- Infection-Associated Mechanisms of Neuro-Inflammation and Neuro-Immune Crosstalk in Chronic Respiratory Diseases.International journal of molecular sciences · 2021Review
- Livestock farm particulate matter enhances airway inflammation in mice with or without allergic airway disease.The World Allergy Organization journal · 2020Article
- Interleukin-31 single nucleotide polymorphisms are significantly associated with endometrial cancer in Chinese Han women.International journal of clinical and experimental pathology · 2018Article
- New perspectives on the regulation of type II inflammation in asthma.F1000Research · 2017Review
- Associations betweenDisease markers · 2017Article
- The association of interleukin-31 polymorphisms with interleukin-31 serum levels and risk of systemic lupus erythematosus.Rheumatology international · 2016Article
- Interleukin-31 expression and relation to disease severity in human asthma.Scientific reports · 2016Article
- The Transforming Growth Factor β1/Interleukin-31 Pathway Is Upregulated in Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure and Is Associated with Disease Severity and Survival.Clinical and vaccine immunology : CVI · 2015Article
- Polymorphisms of interleukin-31 are associated with anti-CCP levels in females with rheumatoid arthritis.Journal of genetics · 2014Article
- Role of IL-31 in regulation of Th2 cytokine levels in patients with nasal polyps.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2014Article
- Interleukin-31: a novel diagnostic marker of allergic diseases.Current allergy and asthma reports · 2014Review
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInterleukin 31 (IL-31) is a T helper type 2 effector cytokine that plays an important role in the pathogenesis of atopic and allergic diseases. IL-31 may be involved in promoting allergic inflammation and in inducing airway epithelial responses such as allergic asthma.
methodsSingle-base extension analysis was used to detect the genotypes of IL-31 single nucleotide polymorphisms (SNPs), and we compared the genotype and allele frequencies of the IL-31 SNPs between patients with asthma and healthy controls.
resultsThere were no significant differences in the genotype and allele frequencies of the IL-31 SNPs between patients with asthma and healthy controls. Furthermore we compared the genotype and allele frequencies of IL-31 SNPs between patients with atopic asthma, those with non-atopic asthma and healthy controls. This showed that the SNPs were not associated with the susceptibility to atopic asthma. There were no significant differences in the haplotype frequencies of IL-31 SNPs between patients with asthma and healthy controls. In patients with asthma, the IL-31 SNPs were significantly correlated with total serum levels of IgE (p=0.035).
conclusionsOur results indicate that, the IL-31 SNPs may be associated with IgE production in patients with asthma.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.