ArticleKorean journal of pathology2012
Clinicopathologic features of q Fever patients with acute hepatitis.
Article in Korean journal of pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Deciphering the "Doxycycline Deficiency Syndrome": Defining the Characteristic Clinical, Laboratory and Imaging Findings in Patients Presenting with Leptospirosis, Q Fever and Rickettsial Diseases in Far North Queensland, Tropical Australia.Tropical medicine and infectious disease · 2026Article
- Bacterial Granulomatous Lung Diseases: Radiological Findings and Differential Diagnosis.Infectious disease reports · 2026Review
- Navigating Q fever: Current perspectives and challenges in outbreak preparedness.Open veterinary journal · 2024Review
- [(Rare) infectious hepatitis as an important differential diagnosis of unclear hepatopathy].Pathologie (Heidelberg, Germany) · 2023Article
- Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants.Frontiers in veterinary science · 2023Article
- Case Report of Acute Q Fever with Hepatitis Progressing to Chronic Q Fever with Endocarditis.Journal of community hospital internal medicine perspectives · 2023Article
- The First Report ofMicroorganisms · 2022Article
- Pathological study and molecular detection of zoonotic diseases in small ruminants at slaughterhouses in Mymensingh, Bangladesh.Veterinary world · 2022Article
- Article
- Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea.Journal of Korean medical science · 2017Article
- Q Fever Presented as a Large Retroperitoneal Pseudotumoral Mass.Case reports in pathology · 2017Article
- From Q Fever to Coxiella burnetii Infection: a Paradigm Change.Clinical microbiology reviews · 2017Review
- Prolonged pyrexia and hepatitis: Q fever.The American journal of medicine · 2014Article
- The First Case of Coxiella Burnetti Infection Detected Through Bone Marrow Biopsy in Vietnam.Clinical pathology (Thousand Oaks, Ventura County, Calif.)Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQ fever caused by Coxiella burnetii presents with diverse clinical and pathological features including subclinical or cholestatic hepatitis. However, the pathological features of liver biopsies from patients with Q fever have not been well described.
methodsClinical features and pathological findings of liver biopsies were reviewed in seven cases of Q fever that were confirmed by serological, microbiological, or molecular tests.
resultsAll cases presented with fever. Liver enzymes were mildly elevated except one case with marked hyperbilirubinemia. Characteristic fibrin ring granulomas were present in three cases, epithelioid granulomas with eosinophilic infiltration in two cases, extensive extravasated fibrins without ring configuration mimicking necrotizing granuloma in one case, and acute cholangitis without granuloma in one case. All cases were treated with antibiotics for 20 days. Six cases were completely cured, but one suffered from multiorgan failure.
conclusionsC. burnetii infection is uncommon, but should always be considered in patients with acute hepatitis and fever. Because variable-sized circumferential or radiating fibrin deposition was a consistent feature of the present cases, Q fever can be strongly suggested by pathological features and confirmed by serological and/or molecular tests.
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