Evidence map›Paper›PMID 23109494›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2013

Spontaneous formation of heterogeneous patches on polymer-lipid core-shell particle surfaces during self-assembly.

Carolina Salvador-Morales, Pedro M Valencia, Weiwei Gao, Rohit Karnik, Omid C Farokhzad

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Interrogating Cellular Functions with Designer Janus Particles.Chemistry of materials : a publication of the American Chemical Society · 2017
    Article
  4. Review
  5. Review
  6. Liposome-like Nanostructures for Drug Delivery.Journal of materials chemistry. B · 2013
    Article
  7. Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carolina Salvador-MoralesDepartment of Anesthesiology, Brigham and Women's Hospital-Harvard Medical School, Boston, MA 02115, USA.
Pedro M Valencia
Weiwei Gao
Rohit Karnik
Omid C Farokhzad

Funding

The Development of Clinical Grade, Targeted Magnetic NanoparticlesU54CA151884 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL · 2010 to 2014
$11.3M
Development of FcRn-Targeted Nanoparticles for Efficient Oral Delivery of InsulinR01EB015419 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI FAROKHZAD, OMID C, KARNIK, ROHIT N · 2012 to 2015
$2.8M
NCI NIH HHS U54 CA151884NCI NIH HHS U54-CA151884NIBIB NIH HHS 1R01EB015419-01NIBIB NIH HHS R01 EB015419
6 · The paper itself

Abstract

Spontaneous formation of heterogeneous patches on the surface of lipid-based nanoparticles (NPs) and microparticles (MPs) due to the segregation of two different functional groups. Patch formation is observed when tracing the functional groups with quantum dots, gold nanoparticles, and fluorescent dyes. This discovery could have important implications for the future design of self-assembled NPs and MPs for different biomedical applications.

Indexed as

LipidsNanoparticlesNanotechnologyParticle SizePolymersSurface PropertiesLipidsPolymers

Identifiers

PMID23109494
PMCPMC4157734

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.