ReviewBirth defects research. Part C, Embryo today : reviews2012
Embryonic wound healing: a primer for engineering novel therapies for tissue repair.
Review in Birth defects research. Part C, Embryo today : reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing.Biology · 2026Review
- Interferon-gamma signaling promotes cartilage regeneration after injury.Scientific reports · 2024Article
- Advanced Hydrogel-Based Strategies for Enhanced Bone and Cartilage Regeneration: A Comprehensive Review.Gels (Basel, Switzerland) · 2023Review
- Middle meningeal artery embolisation: The review of a new treatment for chronic subdural hematomas.Surgical neurology international · 2023Review
- Molecular Mechanisms of Fetal Tendon Regeneration Versus Adult Fibrous Repair.International journal of molecular sciences · 2021Article
- Regenerative Medicine for Equine Musculoskeletal Diseases.Animals : an open access journal from MDPI · 2021Review
- Recapitulation of normal collagen architecture in embryonic wounded corneas.Scientific reports · 2020Article
- Calcium Signaling in Vertebrate Development and Its Role in Disease.International journal of molecular sciences · 2018Review
- Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.Disease models & mechanisms · 2018Article
- Embryonic skin development and repair.Organogenesis · 2018Article
- Chronic Wound Healing: A Review of Current Management and Treatments.Advances in therapy · 2017Review
- Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas.Journal of diabetes research · 2016Article
- Cartilage regeneration for treatment of osteoarthritis: a paradigm for nonsurgical intervention.Therapeutic advances in musculoskeletal disease · 2015Review
- RNA interference mediated JAM-A gene silencing promotes human epidermal stem cell proliferation.Human cell · 2015Article
- Expression and function of connexin 43 in human gingival wound healing and fibroblasts.PloS one · 2015Article
- Calcium-dependent neuroepithelial contractions expel damaged cells from the developing brain.Developmental cell · 2014Article
- Purinergic signaling in early inflammatory events of the foreign body response: modulating extracellular ATP as an enabling technology for engineered implants and tissues.Tissue engineering. Part B, Reviews · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Scar is the default tissue repair used by the body in response to most injuries-a response that occurs in wounds ranging in seriousness from minor skin cuts to complete severance of the spinal cord. By contrast, before the third trimester of pregnancy embryonic mammals tend to heal without scarring due to a variety of mechanisms and factors that are uniquely in operation during development in utero. The goal of tissue engineering is to develop safe and clinically effective biological substitutes that restore, maintain, or improve tissue function in patients. This review provides a comparative overview of wound healing during development and maturation and seeks to provide a perspective on just how much the embryo may be able teach us in the engineering of new therapies for tissue repair.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.