ReviewBirth defects research. Part C, Embryo today : reviews2012
Wound healing in development.
Review in Birth defects research. Part C, Embryo today : reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The potential application of natural products in cutaneous wound healing: A review of preclinical evidence.Frontiers in pharmacology · 2022Pooled it
- Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1BMC biology · 2024Article
- Sprayable biomimetic double mask with rapid autophasing and hierarchical programming for scarless wound healing.Science advances · 2024Article
- Biological scaffold as potential platforms for stem cells: Current development and applications in wound healing.World journal of stem cells · 2024Review
- Composite Hydrogels with Embedded Silver Nanoparticles and Ibuprofen as Wound Dressing.Gels (Basel, Switzerland) · 2023Article
- Determination of the Bioactive Compounds fromMolecules (Basel, Switzerland) · 2023Article
- Review
- Skin biomechanics: a potential therapeutic intervention target to reduce scarring.Burns & trauma · 2022Review
- Hierarchical cluster analysis in the study of the effect of cytokine expression patterns on endometrial repair and receptivity after hysteroscopic adhesiolysis.Annals of translational medicine · 2021Article
- Experimental models and methods for cutaneous wound healing assessment.International journal of experimental pathology · 2020Review
- STAT3 signalling pathway is implicated in keloid pathogenesis by preliminary transcriptome and open chromatin analyses.Experimental dermatology · 2019Article
- The efficacy of fascial granuloma excision with conjunctival autografting after pterygium surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018Article
- Mechanical Forces in Cutaneous Wound Healing: Emerging Therapies to Minimize Scar Formation.Advances in wound care · 2018Review
- Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation.Developmental dynamics : an official publication of the American Association of Anatomists · 2017Article
- An Emergence Framework of Carcinogenesis.Frontiers in oncology · 2017Article
- An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia.Medicine · 2016Article
- Article
- Phototherapy promotes healing of cutaneous wounds in undernourished rats.Anais brasileiros de dermatologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Wound healing is the inherent ability of an organism to protect itself against injuries. Cumulative evidence indicates that the healing process patterns in part embryonic morphogenesis and may result in either organ regeneration or scarring, phenomena that are developmental stage- or age-dependent. Skin is the largest organ. Its morphogenesis and repair mechanisms have been studied extensively due not only to its anatomical location, which allows easy access and observation, but also to its captivating structure and vital function. Thus, this review will focus on using skin as a model organ to illustrate new insights into the mechanisms of wound healing that are developmentally regulated in mammals, with special emphasis on the role of the Wnt signaling pathway and its crosstalk with TGF-β signaling. Relevant information from studies of other organs is discussed where it applies, and the clinical impact from such knowledge and emerging concepts on regenerative medicine are discussed in perspective.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.