ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2013
Sleep disturbances in patients with multiple sclerosis.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03949296 (A Randomized, Placebo-Controlled Study of Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized, Placebo-Controlled Study of Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis
Who cites it
21 citing papers in PubMed.
- Sleep disorders in patients with multiple sclerosis.BMC neurology · 2025Article
- Exploring sleep-related disorders in patients with multiple sclerosis: A questionnaire-based approach.Journal of family medicine and primary care · 2024Article
- Posterior Tibial Nerve Stimulation for the Treatment of Detrusor Overactivity in Multiple Sclerosis Patients: A Narrative Review.Journal of personalized medicine · 2024Review
- Insomnia, Fatigue, Bladder Disorders and Mood Disorders among Polish Patients with Multiple Sclerosis: Cross-Sectional Study.Journal of clinical medicine · 2024Article
- Association between Daytime Sleepiness, Fatigue and Autonomic Responses during Head-Up Tilt Test in Multiple Sclerosis Patients.Brain sciences · 2023Article
- Sleep counts! Role and impact of sleep in the multimodal management of multiple sclerosis.Journal of neurology · 2023Review
- Sleep Disturbances, Degree of Disability and the Quality of Life in Multiple Sclerosis Patients.International journal of environmental research and public health · 2022Article
- Observational
- Insomnia among non-depressed multiple sclerosis patients: a cross-sectional study.The Egyptian journal of neurology, psychiatry and neurosurgery · 2018Article
- Central sleep apnea in multiple sclerosis: a pilot study.Sleep & breathing = Schlaf & Atmung · 2017Article
- Sleep disorders in patients with multiple sclerosis in China.Sleep & breathing = Schlaf & Atmung · 2017Article
- Fatigue and Sleep in Multiple Sclerosis Patients: A Comparison of Self-Report and Performance-Based Measures.Frontiers in neurology · 2017Article
- Relative Importance of Baseline Pain, Fatigue, Sleep, and Physical Activity: Predicting Change in Depression in Adults With Multiple Sclerosis.Archives of physical medicine and rehabilitation · 2016Observational
- Low Prevalence of Sleep Disorders in Demyelinating Disease in a Northern Tenerife Population.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016Article
- Fatigue in multiple sclerosis: a look at the role of poor sleep.Frontiers in neurology · 2015Article
- Melatonin acts as antioxidant and improves sleep in MS patients.Neurochemical research · 2014Article
- Moebius syndrome and narcolepsy: A case dissertation.Sleep science (Sao Paulo, Brazil) · 2014Article
- NAPS-MS: Natalizumab Effects on Parameters of Sleep in Patients with Multiple Sclerosis.International journal of MS careArticle
- Rest-Activity Rhythm, Pain, and Motor Activity in Multiple Sclerosis.International journal of MS careArticle
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep disturbances constitute one of the important yet underestimated aspects of functioning of patients with multiple sclerosis (MS). The objective of this study was to evaluate sleep disturbances in patients with MS, with regard to demographic factors, disease-related variables, co-existing conditions and fatigue. In 100 MS patients, Epworth Sleepiness Scale (ESS) and a questionnaire about sleep disturbances (SlD) were implemented. ESS and SlD results were analyzed with regard to age, gender, duration of MS, type of its course, degree of disability in Expanded Disability Status Scale (EDSS), MS therapies, coexisting diseases, results of Fatigue Severity Scale (FSS) and Modified Fatigue Impact Scale (MFIS). ESS score indicated increased daytime sleepiness in 19 patients. In SlD, 49 subjects reported sleep disturbances and 35 more than one of their kind (most commonly terminal and middle insomnia). No relationships were found between ESS and SlD scores and age, gender, MS duration, type of its course, EDSS or coexisting diseases. In 36 patients, somatic complaints interfered with sleep. The patients with depression had significantly lower ESS result and those currently treated with immunomodulation had significantly lower SlD score. SlD score correlated positively with FSS and MFIS. Sleep disturbances in MS patients may occur independently from demographic and disease-related variables, but they are often influenced by the symptoms of MS and therapies used. Sleep disturbances may contribute to fatigue in the course of MS.
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