ReviewAmino acids2013
Cationic membrane peptides: atomic-level insight of structure-activity relationships from solid-state NMR.
Review in Amino acids, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Article
- Solid-State NMR of Virus Membrane Proteins.Accounts of chemical research · 2025Article
- Self-Exfoliated Guanidinium Covalent Organic Nanosheets as High-Capacity Curcumin Carrier.Biomimetics (Basel, Switzerland) · 2024Article
- Nanofibrous MultiDomain Peptide Hydrogels Provide T Cells a 3D, Cytocompatible Environment for Cell Expansion and Antigen-Specific Killing.ACS biomaterials science & engineering · 2024Article
- Structural and pKa Estimation of the Amphipathic HR1 in SARS-CoV-2: Insights from Constant pH MD, Linear vs. Nonlinear Normal Mode Analysis.International journal of molecular sciences · 2023Article
- From Angstroms to Nanometers: Measuring Interatomic Distances by Solid-State NMR.Chemical reviews · 2022Review
- Preliminary Characterization of NP339, a Novel Polyarginine Peptide with Broad Antifungal Activity.Antimicrobial agents and chemotherapy · 2021Article
- Structure Elucidation and Functional Studies of a Novel β-hairpin Antimicrobial Peptide from the Marine PolychaetaMarine drugs · 2020Article
- Identification and elucidation of proline-rich antimicrobial peptides with enhanced potency and delivery.Biotechnology and bioengineering · 2019Article
- Oligomeric Structure and Three-Dimensional Fold of the HIV gp41 Membrane-Proximal External Region and Transmembrane Domain in Phospholipid Bilayers.Journal of the American Chemical Society · 2018Article
- Insights into Membrane Translocation of Protegrin Antimicrobial Peptides by Multistep Molecular Dynamics Simulations.ACS omega · 2018Article
- Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.Toxins · 2017Article
- Interaction of Scots Pine Defensin with Model Membrane by Coarse-Grained Molecular Dynamics.The Journal of membrane biology · 2017Article
- Charge Distribution Fine-Tunes the Translocation of α-Helical Amphipathic Peptides across Membranes.Biophysical journal · 2016Article
- Cm-p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae).FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015Article
- Action of the multifunctional peptide BP100 on native biomembranes examined by solid-state NMR.Journal of biomolecular NMR · 2015Article
- Cardiolipin interaction with subunit c of ATP synthase: solid-state NMR characterization.Biochimica et biophysica acta · 2015Article
- Molecular dynamics of neutral polymer bonding agent (NPBA) as revealed by solid-state NMR spectroscopy.Molecules (Basel, Switzerland) · 2014Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Many membrane-active peptides, such as cationic cell-penetrating peptides (CPPs) and antimicrobial peptides (AMPs), conduct their biological functions by interacting with the cell membrane. The interactions of charged residues with lipids and water facilitate membrane insertion, translocation or disruption of these highly hydrophobic species. In this review, we will summarize high-resolution structural and dynamic findings towards the understanding of the structure-activity relationship of lipid membrane-bound CPPs and AMPs, as examples of the current development of solid-state NMR (SSNMR) techniques for studying membrane peptides. We will present the most recent atomic-resolution structure of the guanidinium-phosphate complex, as constrained from experimentally measured site-specific distances. These SSNMR results will be valuable specifically for understanding the intracellular translocation pathway of CPPs and antimicrobial mechanism of AMPs, and more generally broaden our insight into how cationic macromolecules interact with and cross the lipid membrane.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.