Trial reportDigestive diseases and sciences2013
Image-enhanced endoscopy with I-scan technology for the evaluation of duodenal villous patterns.
Trial report in Digestive diseases and sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04349904 (Near-Focus Narrow Band Imaging Classification of Villous Atrophy in Suspected Coeliac Disease), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Near-Focus Narrow Band Imaging Classification of Villous Atrophy in Suspected Coeliac Disease: International Development and Validation
Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Risk Factors for Mucosal Redness in the Duodenal Bulb as Detected via Linked Color Imaging.Diagnostics (Basel, Switzerland) · 2024Article
- Endoscope Capsules: The Present Situation and Future Outlooks.Bioengineering (Basel, Switzerland) · 2023Review
- Celiac Disease Revisited.GE Portuguese journal of gastroenterology · 2022Review
- Electronic chromo-endoscopy: technical details and a clinical perspective.Translational gastroenterology and hepatology · 2022Review
- Factors associated with number of duodenal samples obtained in suspected celiac disease.Endoscopy international open · 2017Article
- Cost effectiveness of routine duodenal biopsies in iron deficiency anemia.World journal of gastroenterology · 2016Article
- Endoscopic evaluation of celiac disease.Endoscopy international open · 2016Article
- High definition i-SCAN endoscopy with water immersion technique accurately reflects histological severity of celiac disease.Endoscopy international open · 2016Article
- Seronegative Celiac Disease and Immunoglobulin Deficiency: Where to Look in the Submerged Iceberg?Nutrients · 2015Review
- Dyspepsia and celiac disease: Prevalence, diagnostic tools and therapy.World journal of methodology · 2014Review
- Endoscopic tools for the diagnosis and evaluation of celiac disease.World journal of gastroenterology · 2013Review
- Detection of villous atrophy using endoscopic images for the diagnosis of celiac disease.Digestive diseases and sciences · 2013Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundI-scan technology is the newly developed endoscopic tool that works in real time and utilizes a digital contrast method to enhance endoscopic image.
aimsWe performed a feasibility study aimed to determine the diagnostic accuracy of i-scan technology for the evaluation of duodenal villous patterns, having histology as the reference standard.
methodsIn this prospective, single center, open study, patients undergoing upper endoscopy for an histological evaluation of duodenal mucosa were enrolled. All patients underwent upper endoscopy using high resolution view in association with i-scan technology. During endoscopy, duodenal villous patterns were evaluated and classified as normal, partial villous atrophy, or marked villous atrophy. Results were then compared with histology.
resultsOne hundred fifteen subjects were recruited in this study. The endoscopist was able to find marked villous atrophy of the duodenum in 12 subjects, partial villous atrophy in 25, and normal villi in the remaining 78 individuals. The i-scan system was demonstrated to have great accuracy (100 %) in the detection of marked villous atrophy patterns. I-scan technology showed quite lower accuracy in determining partial villous atrophy or normal villous patterns (respectively, 90 % for both items).
conclusionsImage-enhancing endoscopic technology allows a clear visualization of villous patterns in the duodenum. By switching from the standard to the i-scan view, it is possible to optimize the accuracy of endoscopy in recognizing villous alteration in subjects undergoing endoscopic evaluation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.