Evidence map›Paper›PMID 23108498›Full record

ReviewReviews in endocrine & metabolic disorders2012

Molecular and functional aspects of menstruation in the macaque.

Robert M Brenner, Ov D Slayden

Open access · hybridAbstract readReview
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Bats as instructive animal models for studying longevity and aging.Annals of the New York Academy of Sciences · 2024
    Review
  4. Review
  5. Article
  6. Mechanisms of Regeneration and Fibrosis in the Endometrium.Annual review of cell and developmental biology · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Effects of marijuana on reproductive health: preconception and gestational effects.Current opinion in endocrinology, diabetes, and obesity · 2021
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Endometrial Stem Cell Markers: Current Concepts and Unresolved Questions.International journal of molecular sciences · 2018
    Review
  17. Why primate models matter.American journal of primatology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Robert M BrennerDivision of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA. brennerr@ohsu.edu
Ov D Slayden
Oregon Health & Science University · USOregon National Primate Research Center · US

Funding

YR 50 PROJ- ROBERTS PRIMATE ISLETP51RR000163 · NCRR · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI PICKER, LOUIS J. · 1985 to 2011
$140.8M
VASOACTIVE FACTORS IN ART CYCLES AND OVARIAN HYPERSTIMULATION SYNDROMEU54HD018185 · NICHD · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI STOUFFER, RICHARD L · 1999 to 2010
$13.8M
Suppression of Breakthrough Bleeding in LNG-IUS UsersR01HD043209 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SLAYDEN, OV D · 2002 to 2006
$1.7M
REPRODUCTIVE STEROIDS AND EXPERIMENTAL STROKEK01RR000163 · NCRR · OREGON HEALTH AND SCIENCE UNIVERSITY · PI MURPHY, STEPHANIE J · 2000 to 2004
$479k
REPRODUCTIVE BIOLOGY IN PRIMATES: CENTER FACILITIESP30HD018185 · NICHD · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI SPINDEL, ELIOT R · 1985 to 1998
–
NCRR NIH HHS K01 RR000163NCRR NIH HHS P51 RR000163NCRR NIH HHS RR00163NICHD NIH HHS HD18185NICHD NIH HHS HD43209NICHD NIH HHS P30 HD018185NICHD NIH HHS R01 HD043209NICHD NIH HHS U54 HD018185
6 · The paper itself

Abstract

Much of our understanding of the molecular control of menstruation arises from laboratory models that experimentally recapitulate some, but not all, aspects of uterine bleeding observed in women. These models include: in vitro culture of endometrial explants or isolated endometrial cells, transplantation of human endometrial tissue into immunodeficient mice and the induction of endometrial breakdown in appropriately pretreated mice. Each of these models has contributed to our understanding of molecular and cellular mechanisms of menstruation, but nonhuman primates, especially macaques, are the animal model of choice for evaluating therapies for menstrual disorders. In this chapter we review some basic aspects of menstruation, with special emphasis on the macaque model and its relevance to the clinical issues of irregular and heavy menstrual bleeding (HMB).

Indexed as

AnimalsEndometriumFemaleHumansMacacaMenstruationMenstruation DisturbancesPhylogenyUterus

Identifiers

PMID23108498
PMCPMC3523117
OpenAlexW2005680123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.