Evidence map›Paper›PMID 23108147›Full record

Trial reportObesity facts2012

Insulin resistance predicts the effectiveness of different glycemic index diets on weight loss in non-obese women.

Mauro Felippe Felix Mediano, Rosely Sichieri

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity facts, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Low glycaemic index diets for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2017
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mauro Felippe Felix MedianoDepartment of Clinical and Experimental Medicine, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro, Brazil. mffmediano@gmail.com
Rosely Sichieri

Funding

Primary Prevention of Weight Gain for Women Aged 25-45R03TW005773 · FIC · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI WILLETT, WALTER C. · 2002 to 2004
$119k
FIC NIH HHS R03 TW005773FIC NIH HHS R03 TW005773-03
6 · The paper itself

Abstract

objectiveThe present study aimed to evaluate whether baseline insulin resistance (IR) modify weight change associated to glycemic index (GI) of the diet.

methodThis is a secondary analysis of a randomized GI intervention according to baseline HOMA-IR. Middle-aged (25-45 years), non-obese (BMI 23-29.9 kg/m²) women were randomized to low or high GI diets matched on total energy, macronutrient composition, and fiber content. Both groups received dietary counseling based on a small energy restriction (100-300 kcal/day). Women were classified in two groups according to their baseline HOMA-IR: IR (n = 64) and non-IR (n = 121).

resultsAt baseline, IR and non-IR groups had similar BMI (26.7 vs. 26.3 kg/m²; p = 0.21), but the IR group presented with higher waist circumference (82.7 vs. 80.8 cm; p = 0.02) and showed greater weight loss after 12 months of follow-up (-1.6 vs. -1.1 kg; p = 0.01), mainly among those in a high-GI diet (-2.1 vs. -1.0 kg; p = 0.005) compared to the non-IR group (-1.4 vs. -0.8 kg; p = 0.04).

conclusionsThe high-GI group showed statistically significant higher reduction in body weight, mainly among those women with baseline IR . Low-GI diet did not facilitate weight loss neither in IR women nor in non-IR women.

Indexed as

Glycemic IndexInsulin ResistanceAdultBody Mass IndexDietary CarbohydratesDietary FiberDiet, ReducingEnergy IntakeFemaleHumansMiddle AgedOverweightTreatment OutcomeWaist CircumferenceWeight LossDietary CarbohydratesDietary Fiber

Identifiers

PMID23108147
PMCPMC6902216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.