ReviewJournal of biosciences2012
Complex genetic origin of Indian populations and its implications.
Review in Journal of biosciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model.BMC genetics · 2015Pooled it
- Congenital Hyperinsulinism India Association: An Approach to Address the Challenges and Opportunities of a Rare Disease.Medical sciences (Basel, Switzerland) · 2025Review
- Precision nutrition across climates: decoding diet, tradition, and genomic adaptations from South Asia to the Arctic.Frontiers in nutrition · 2025Review
- Article
- South Asia: The Missing Diverse in Diversity.Behavior genetics · 2024Review
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- Advancements and Challenges in Ancient DNA Research: Bridging the Global North-South Divide.Genes · 2023Review
- Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol.BMJ open · 2022Article
- Rare disease patients in India are rarely involved in international orphan drug trials.PLOS global public health · 2022Article
- Pediatric inflammatory bowel disease: Is it really uncommon in Asian children?JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- The role of patient organizations in the rare disease ecosystem in India: an interview based study.Orphanet journal of rare diseases · 2019Article
- Spectrum of genomic variations in Indian patients with progressive familial intrahepatic cholestasis.BMC gastroenterology · 2018Article
- Identification of a case ofThe Indian journal of medical research · 2018Article
- Designing genetic association studies for complex traits in India.The Indian journal of medical research · 2017Article
- Genetic variations in the Dravidian population of South West coast of India: Implications in designing case-control studies.The Indian journal of medical research · 2017Article
- Unraveling the Population History of Indian Siddis.Genome biology and evolution · 2017Article
- Environmental selection influences the diversity of TLR genes in ethnic Rajbanshi population of North Bengal Region of India.Journal, genetic engineering & biotechnology · 2016Article
- Inflammatory bowel disease in India - Past, present and future.World journal of gastroenterology · 2016Review
- TMC-SNPdb: an Indian germline variant database derived from whole exome sequences.Database : the journal of biological databases and curation · 2016Article
- Influence of dihydrofolate reductase gene polymorphisms rs408626 (-317A>G) and rs442767 (-680C>A) on the outcome of methotrexate-based maintenance therapy in South Indian patients with acute lymphoblastic leukemia.European journal of clinical pharmacology · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Indian populations are classified into various caste, tribe and religious groups, which altogether makes them very unique compared to rest of the world. The long-term firm socio-religious boundaries and the strict endogamy practices along with the evolutionary forces have further supplemented the existing high-level diversity. As a result, drawing definite conclusions on its overall origin, affinity, health and disease conditions become even more sophisticated than was thought earlier. In spite of these challenges, researchers have undertaken tireless and extensive investigations using various genetic markers to estimate genetic variation and its implication in health and diseases. We have demonstrated that the Indian populations are the descendents of the very first modern humans, who ventured the journey of out-of-Africa about 65,000 years ago. The recent gene flow from east and west Eurasia is also evident. Thus, this review attempts to summarize the unique genetic variation among Indian populations as evident from our extensive study among approximately 20,000 samples across India.
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