ArticleBMC public health2012
Effects of manganese on routine semen quality parameters: results from a population-based study in China.
Article in BMC public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 45 citations in OpenAlex.
- Associations of seminal plasma metal mixtures with sperm quality parameters and exploratory mediation analysis of urinary oxidative stress biomarkers: a cross-sectional study from the RHCC-AC preconception cohort.Frontiers in endocrinology · 2026Article
- Multielemental Profile for Seminal Plasma Through Inductively Coupled Plasma-Tandem Mass Spectrometry and Its Relationship with Seminal Parameters, Spermatic Biomarkers, and Oxidative Stress.Antioxidants (Basel, Switzerland) · 2025Article
- ZIP8 Is Upregulated in the Testis ofNutrients · 2024Article
- Consequences of Disturbing Manganese Homeostasis.International journal of molecular sciences · 2023Review
- Occupational Exposure to Physical and Chemical Risk Factors: A Systematic Review of Reproductive Pathophysiological Effects in Women and Men.Safety and health at work · 2023Review
- An Overview of Essential Microelements and Common Metallic Nanoparticles and Their Effects on Male Fertility.International journal of environmental research and public health · 2022Review
- Selenium supplementation influences mice testicular selenoproteins driven by gut microbiota.Scientific reports · 2022Article
- Impact of Heavy Metals on Human Male Fertility-An Overview.Antioxidants (Basel, Switzerland) · 2021Review
- Diet and Nutritional Factors in Male (In)fertility-Underestimated Factors.Journal of clinical medicine · 2020Review
- Antioxidant activity of Coridius chinensis extracts on manganese-induced testicular damage in rats.Environmental toxicology · 2019Article
- Associations between occupation exposure to Formaldehyde and semen quality, a primary study.Scientific reports · 2015Article
- Urgent need to reevaluate the latest World Health Organization guidelines for toxic inorganic substances in drinking water.Environmental health : a global access science source · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundManganese (Mn) is an essential element in humans but its effect on semen quality is unclear. This study therefore aimed to assess the effects of Mn on semen quality in healthy men with no occupational exposure to Mn.
methodsSemen samples were obtained from healthy Chinese men 20-59 years old who were recruited from six provinces in China. Individuals with urogenital tract diseases, tuberculosis, or occupational exposure to heavy metals were excluded. A questionnaire survey was conducted, and the external genitalia, semen quality, and serum Mn levels were examined.
resultsA total of 1,179 volunteers were enrolled in this study. The median serum Mn concentration was 8.2 μg/L (25th percentile (P25)=3.7 μg/L, P75=16.2 μg/L). After adjusted area (six provinces), abstinence interval, season, registered residence, age of subjects, education level, income, smoking, and drinking, the risk of teratospermia was increased at serum Mn concentrations >19.40 μg/L (P80) group, with an adjusted odds ratio of 2.27 (95% confidence interval: 1.18-4.37).
conclusionHigh serum Mn levels appeared to have harmful effects on sperm morphology and motility among healthy men with no occupational exposure to Mn.
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Registered trials
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