ArticleBMC veterinary research2012
High diversity of genetic lineages and virulence genes in nasal Staphylococcus aureus isolates from donkeys destined to food consumption in Tunisia with predominance of the ruminant associated CC133 lineage.
Article in BMC veterinary research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mupirocin-resistantAntimicrobial resistance and infection control · 2018Pooled it
- Prevalence, Antimicrobial Resistance, and Virulence Potential ofAntibiotics (Basel, Switzerland) · 2025Article
- Molecular Characterization of ChimericMicroorganisms · 2024Article
- Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): antimicrobial-resistantEFSA journal. European Food Safety Authority · 2022Article
- Aerobic Commensal Conjunctival Microflora in Healthy Donkeys.Animals : an open access journal from MDPI · 2022Article
- Shared antibiotic resistance and virulence genes in Staphylococcus aureus from diverse animal hosts.Scientific reports · 2022Article
- A One Health Approach Molecular Analysis ofAntibiotics (Basel, Switzerland) · 2022Article
- First Report of Antimicrobial Susceptibility and Virulence Gene Characterization Associated withAnimals : an open access journal from MDPI · 2021Article
- Article
- Genetic characterisation of staphylococci of food-producing animals in Senegal. PVL detection among MSSA.BMC veterinary research · 2019Article
- Molecular Characterization of EquineToxins · 2019Article
- Antimicrobial Resistance among Staphylococci of Animal Origin.Microbiology spectrum · 2018Review
- Identification of a staphylococcal complement inhibitor with broad host specificity in equidThe Journal of biological chemistry · 2018Article
- Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus.Scientific reports · 2017Article
- Genetic Diversity and Virulence Potential of Staphylococcus aureus Isolated from Crayfish (Procambarus clarkii).Current microbiology · 2017Article
- Staphylococcus aureus in Animals and Food: Methicillin Resistance, Prevalence and Population Structure. A Review in the African Continent.Microorganisms · 2016Review
- Article
- Carriage of Staphylococcus aureus by free-living wild animals in Spain.Applied and environmental microbiology · 2014Article
- Detection of methicillin-susceptible Staphylococcus aureus ST398 and ST133 strains in gut microbiota of healthy humans in Spain.Microbial ecology · 2013Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to determine the genetic lineages and the incidence of antibiotic resistance and virulence determinants of nasal Staphylococcus aureus isolates of healthy donkeys destined to food consumption in Tunisia.
resultsNasal swabs of 100 donkeys obtained in a large slaughterhouse in 2010 were inoculated in specific media for S. aureus and methicillin-resistant S. aureus (MRSA) recovery. S. aureus was obtained in 50% of the samples, being all of isolates methicillin-susceptible (MSSA). Genetic lineages, toxin gene profile, and antibiotic resistance mechanisms were determined in recovered isolates. Twenty-five different spa-types were detected among the 50 MSSA with 9 novel spa-types. S. aureus isolates were ascribed to agr type I (37 isolates), III (7), II (4), and IV (2). Sixteen different sequence-types (STs) were revealed by MLST, with seven new ones. STs belonging to clonal clomplex CC133 were majority. The gene tst was detected in 6 isolates and the gene etb in one isolate. Different combinations of enterotoxin, leukocidin and haemolysin genes were identified among S. aureus isolates. The egc-cluster-like and an incomplete egc-cluster-like were detected. Isolates resistant to penicillin, erythromycin, fusidic acid, streptomycin, ciprofloxacin, clindamycin, tetracycline, or chloramphenicol were found and the genes blaZ, erm(A), erm(C), tet(M), fusC were identified.
conclusionsThe nares of donkeys frequently harbor MSSA. They could be reservoirs of the ruminant-associated CC133 lineage and of toxin genes encoding TSST-1 and other virulence traits with potential implications in public health. CC133 seems to have a broader host distribution than expected.
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