Evidence map›Paper›PMID 23107104›Full record

ReviewOral diseases2013

Oral chronic graft-versus-host disease: current pathogenesis, therapy, and research.

J W Mays, H Fassil, D A Edwards, S Z Pavletic, C W Bassim

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Oral diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01851382 completednot on this map

Collection of Saliva and/ or Peripheral Blood From Healthy Volunteers for Research

TypeobservationalSponsorNational Cancer Institute (NCI)Ran2013 to 2015Enrolled29ConditionsGraft vs Host Disease, Healthy Volunteer, Graft-Versus-Host Disease
NCT03602599 completednot on this mapstarted 2018, after this paper: background citation

Natural History of Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls

TypeobservationalSponsorNational Institute of Dental and Craniofacial Research (NIDCR)Ran2018 to 2026Enrolled190ConditionsGraft Versus Host Disease
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Longitudinal assessment and predictors of subjective taste change after hematopoietic cell transplantation (HCT).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  6. Article
  7. Observational
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J W MaysClinical Research Core, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892-4320, USA. maysjw@mail.nih.gov
H Fassil
D A Edwards
S Z Pavletic
C W Bassim

Funding

Immunobiology and therapy of oral mucosal and salivary gland chronic graft-versus-host diseaseZIADE000747 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI MAYS, JACQUELINE · 2016 to 2025
$14.9M
Intramural NIH HHS Z99 DA999999Intramural NIH HHS Z99 DE999999Intramural NIH HHS Z99 OD999999
6 · The paper itself

Abstract

Optimal management of complex autoimmune diseases requires a multidisciplinary medical team including dentists to care for lesions of the oral cavity. In this review, we discuss the presentation, prevalence, diagnosis, and treatment of oral manifestations in chronic graft-versus-host disease (cGVHD), which is a major late complication in patients treated by allogeneic hematopoietic stem cell transplantation. We assess current general knowledge of systemic and oral cGVHD and present general treatment recommendations based on literature review and our clinical experience. Additionally, we review areas where the understanding of oral cGVHD could be improved by further research and address tools with which to accomplish the long-term goal of providing better health and quality of life to patients with cGVHD.

Indexed as

Autoimmune DiseasesGraft vs Host DiseaseMouth DiseasesB-LymphocytesCarcinoma, Squamous CellChronic DiseaseDendritic CellsHematopoietic Stem Cell TransplantationHumansImmunosuppressive AgentsMouth MucosaMouth NeoplasmsRange of Motion, ArticularSalivary GlandsSalivary Proteins and PeptidesT-LymphocytesImmunosuppressive AgentsSalivary Proteins and Peptides

Identifiers

PMID23107104
PMCPMC3561479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.