Trial reportInternational dental journal2012
Arrest of non-cavitated dentinal occlusal caries by sealing pits and fissures: a 36-month, randomised controlled clinical trial.
Trial report in International dental journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Interventions for treating cavitated or dentine carious lesions.The Cochrane database of systematic reviews · 2021Pooled it
- Resin-based sealing vs resin-modified glass-ionomer filling for treatment of occlusal cavitated dentine caries lesions in primary molars - a multi-center randomized controlled split-mouth 3-year follow-up clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Trial
- 24-month efficacy of bioactive versus fluoride sealant for non-cavitated occlusal caries in adults: a randomized clinical trial.Scientific reports · 2025Trial
- Sealing versus partial caries removal in primary molars: a randomized clinical trial.BMC oral health · 2014Trial
- Hydrophobic or hydrophilic fissure sealants: A systematic review and meta-analysis.Dental research journal · 2026Review
- The Assessment of Resin-Based Composite Sealants' Effectiveness in Arresting Non-Cavitated Dentin Carious Lesions (ICDAS 3)-A 12 Month Follow-Up Preliminary Study.Medicina (Kaunas, Lithuania) · 2024Article
- Dental Caries and Its Management.International journal of dentistry · 2023Review
- A concise review of dental sealants in caries management.Frontiers in oral health · 2023Review
- The Assessment of Sealants' Effectiveness in Arresting Non-Cavitated Caries Lesion-A 24-Month Follow-Up.Healthcare (Basel, Switzerland) · 2022Article
- Flexural Strength, Elastic Modulus and Remineralizing Abilities of Bioactive Resin-Based Dental Sealants.Polymers · 2021Article
- Minimally Invasive Therapies for the Management of Dental Caries-A Literature Review.Dentistry journal · 2021Review
- Knowledge and opinions of French dental students related to caries risk assessment and dental sealants (preventive and therapeutic).Odontology · 2021Article
- Quaternary ammonium compound as antimicrobial agent in resin-based sealants.Clinical oral investigations · 2020Article
- Pit and Fissure Sealants-A Comprehensive Review.Dentistry journal · 2018Review
- The Use of Pit and Fissure Sealants-A Literature Review.Dentistry journal · 2017Review
- Marginal and internal analysis of preheated dental fissure-sealing materials using optical coherence tomography.International dental journal · 2016Article
- Managing caries: the need to close the gap between the evidence base and current practice.British dental journal · 2015Article
- Detecting and treating occlusal caries lesions: a cost-effectiveness analysis.Journal of dental research · 2015Article
- Prevalence of dental caries and fissure sealants in a Portuguese sample of adolescents.PloS one · 2015Article
- Minimal intervention dentistry in the management of the paediatric patient.British dental journal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to evaluate the progression of sealed non-cavitated dentinal occlusal caries in a randomised controlled clinical trial. MATERIALS AND
methodsSixty teeth with non-cavitated dentinal occlusal caries were selected in patients with a high risk for caries. Patients were randomly divided into two groups so that each group included 30 teeth. Patients in the experiment group were given oral hygiene instructions and a fissure sealant. Patients in the control group were given oral hygiene instructions only. Caries progression and sealant loss were monitored over a period of 36 months by clinical and radiographic examinations.
resultsClinical and radiographic progression of caries was significantly more frequent in the control group than in the experiment group. Three teeth lost their sealant and showed caries progression, but this was apparent only at the 12-month follow-up. At the 24- and 36-month recall appointments, neither sealant loss nor caries progression were observed.
conclusionThe pit and fissure sealant utilised in this study was shown to be effective in arresting carious lesions at 36 months.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.