ArticleBMC medicine2012
Prevalence and incidence density rates of chronic comorbidity in type 2 diabetes patients: an exploratory cohort study.
Article in BMC medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Global prevalence of multimorbidity among people living with type 2 diabetes: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- The Influence of Diabetes Mellitus on Patients Undergoing Primary Total Lower Extremity Arthroplasty: A Systematic Review and Meta-Analysis.BioMed research international · 2020Pooled it
- Quantifying the effects of diuretics and β-adrenoceptor blockers on glycaemic control in diabetes mellitus - a systematic review and meta-analysis.British journal of clinical pharmacology · 2015Pooled it
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- Healthcare inequalities in general practice due to educational level: A retrospective cohort study analysing patients' presentation and GP response to requests.The European journal of general practice · 2026Article
- A network-based study reveals multimorbidity patterns in people with type 2 diabetes.iScience · 2023Article
- Multimorbidity, Treatment, and Determinants among Chronic Patients Attending Primary Health Facilities in Tshwane, South Africa.Diseases (Basel, Switzerland) · 2023Article
- Factors associated with diabetes concordant comorbidities among adult diabetic patients in Central Ethiopia: a cross-sectional study.Frontiers in clinical diabetes and healthcare · 2023Article
- The impact of an intensive care unit admission on the health status of relatives of intensive care survivors: A prospective cohort study in primary care.The European journal of general practice · 2022Article
- Periodic screening for breast and cervical cancer in women with diabetes: a population-based cohort study.Cancer causes & control : CCC · 2022Article
- Incremental Healthcare Resource Utilization and Expenditures Associated with Cardiovascular Diseases in Patients with Diabetes: A Cross-Sectional Study.Iranian journal of medical sciences · 2022Article
- A Review of Interventional Trials in Youth-Onset Type 2 Diabetes: Challenges and Opportunities.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021Review
- Characterizing Multimorbidity from Type 2 Diabetes: Insights from Clustering Approaches.Endocrinology and metabolism clinics of North America · 2021Review
- Occurrence of comorbidities in newly diagnosed type 2 diabetes patients and their impact after 11 years' follow-up.Scientific reports · 2021Article
- Managing diabetes mellitus with comorbidities in primary healthcare facilities in urban settings: a qualitative study among physicians in Odisha, India.BMC family practice · 2021Article
- Diabetes Concordant Comorbidities and Associated Factors Among Adult Diabetic Out-Patients at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: a Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Associations of Thyroid Hormone Levels and Macrovascular Complications in Euthyroid Type 2 Diabetic Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
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- Type 2 Diabetes Mellitus Related Distress in Thailand.International journal of environmental research and public health · 2020Article
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7 authors.
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Abstract
backgroundEvidence-based diabetes guidelines generally neglect comorbidity, which may interfere with diabetes management. The prevalence of comorbidity described in patients with type 2 diabetes (T2D) shows a wide range depending on the population selected and the comorbid diseases studied. This exploratory study aimed to establish comorbidity rates in an unselected primary-care population of patients with T2D.
methodsThis was a cohort study of 714 adult patients with newly diagnosed T2D within the study period (1985-2007) in a practice-based research network in the Netherlands. The main outcome measures were prevalence and incidence density rates of chronic comorbid diseases and disease clusters. All chronic disease episodes registered in the practice-based research network were considered as comorbidities. We categorised comorbidity into 'concordant' (that is, shared aetiology, risk factors, and management plans with diabetes) and 'discordant' comorbidity. Prevalence and incidence density were assessed for both categories of comorbidity.
resultsThe mean observation period was 17.3 years. At the time of diabetes diagnosis, 84.6% of the patients had one or more chronic comorbid disease of 'any type', 70.6% had one or more discordant comorbid disease, and 48.6% and 27.2% had three or more chronic comorbid diseases of 'any type' or of 'discordant only', respectively. A quarter of those without any comorbid disease at the time of their diabetes diagnosis developed at least one comorbid disease in the first year afterwards. Cardiovascular diseases (considered concordant comorbidity) were the most common, but there were also high rates of musculoskeletal and mental disease. Discordant comorbid diseases outnumbered concordant diseases.
conclusionsWe found high prevalence and incidence density rates for both concordant and discordant comorbidity. The latter may interfere with diabetes management, thus future research and clinical practice should take discordant comorbidity in patients with T2D into account.
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