ArticleJournal of neurogastroenterology and motility2012
Rectal hyposensitivity.
Article in Journal of neurogastroenterology and motility, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- The Italian Unitary Society of Colon-Proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of obstructed and ineffective defecation syndrome.Annals of coloproctology · 2026Guideline
- [Clinical practice guidelines: Irritable bowel syndrome with constipation and functional constipation in adults: Concept, diagnosis, and healthcare continuity. (Part 1 of 2)].Atencion primaria · 2017Guideline
- Elobixibat improves rectal sensation in patients with chronic constipation aged ≥60 years: a randomised placebo-controlled study.BMJ open gastroenterology · 2023Trial
- Effects of Translumbosacral Neuromodulation Therapy on Gut and Brain Interactions and Anorectal Neuropathy in Fecal Incontinence: A Randomized Study.Neuromodulation : journal of the International Neuromodulation Society · 2021Trial
- A Novel Application of Inhibitory Learning Theory: Pediatric Retentive Encopresis.Clinical child and family psychology review · 2026Article
- Sensation of Incomplete Evacuation in Patients With Fecal Incontinence: A Cross-Sectional Study of a Tertiary Referral Cohort.Neurogastroenterology and motility · 2026Article
- Biomarker expression level changes within rectal gut-associated lymphoid tissues in spinal cord-injured rats.ImmunoHorizons · 2025Article
- Article
- Influence of the examination position and distension medium on the rectal sensory test in patients with functional constipation.BMC gastroenterology · 2024Article
- Rectal Sensory and Compliance Testing: A Method Comparison Study between High-Resolution Anorectal Manometry and Barostat Investigations.Diagnostics (Basel, Switzerland) · 2024Article
- Association of delivery mode and number of pregnancies with anorectal manometry data in patients with postpartum constipation.BMC pregnancy and childbirth · 2023Article
- Colonic TRPV4 overexpression is related to constipation severity.BMC gastroenterology · 2023Article
- Effects of Age and Sex on the Anorectal Sensory Threshold to Electrical Stimulation: A Single-center Observational Study.Journal of the anus, rectum and colon · 2023Article
- Clinical significance and related factors of rectal hyposensitivity in patients with functional defecation disorder.Frontiers in medicine · 2023Article
- Rectal Distension Increased the Rectoanal Gradient in Patients with Normal Rectal Sensory Function.Digestive diseases and sciences · 2021Article
- Review
- Scientific solution to a complex problem: physiology and multidisciplinary team improve understanding and outcome in chronic constipation and faecal incontinence.Pediatric surgery international · 2020Article
- Diagnostic value of the balloon expulsion test compared with anorectal manometry in Indian patients with dyssynergic defecation.Przeglad gastroenterologiczny · 2020Article
- Impaired Anorectal Afferents Is a Potential Pathophysiological Factor Associated to Functional Anorectal Pain.Frontiers in neurology · 2020Article
- Defective Conduction of Anorectal Afferents Is a Very Prevalent Pathophysiological Factor Associated to Fecal Incontinence in Women.Journal of neurogastroenterology and motility · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Impaired or blunted rectal sensation, termed rectal hyposensitivity (RH), which is defined clinically as elevated sensory thresholds to rectal balloon distension, is associated with disorders of hindgut function, characterised primarily by symptoms of constipation and fecal incontinence. However, its role in symptom generation and the pathogenetic mechanisms underlying the sensory dysfunction remain incompletely understood, although there is evidence that RH may be due to 'primary' disruption of the afferent pathway, 'secondary' to abnormal rectal biomechanics, or to both. Nevertheless, correction of RH by various interventions (behavioural, neuromodulation, surgical) is associated with, and may be responsible for, symptomatic improvement. This review provides a contemporary overview of RH, focusing on diagnosis, clinical associations, pathophysiology, and treatment paradigms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.