Evidence map›Paper›PMID 23105986›Full record

ArticleIranian Red Crescent medical journal2012

A Comparison of Blood-lead Level (BLL) in Opium-dependant Addicts With Healthy Control Group Using the Graphite Furnace/atomic Absorption Spectroscopy (GF-AAS) Followed by Chemometric Analysis.

Mojtaba Amiri, Ramin Amini

Open access · greenAbstract read
In one paragraph

Article in Iranian Red Crescent medical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts.International journal of preventive medicine · 2021
    Article
  7. Treatment of opium addiction in persian medicine: A review study.Journal of education and health promotion · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Lead Poisoning in Opium Abuser in Iran: A Systematic Review.International journal of preventive medicine · 2018
    Review
  12. Lead poisoning among opium users in Iran: an emerging health hazard.Substance abuse treatment, prevention, and policy · 2017
    Article
  13. Evaluation of blood lead level in methamphetamine users in Tehran.Substance abuse treatment, prevention, and policy · 2017
    Article
  14. Article
  15. Article
  16. Blood lead level in opium dependents and its association with anemia: A cross-sectional study from the capital of Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mojtaba AmiriYoung Researchers Club, Islamic Azad University, Shahr-e-Qods Branch, Tehran, IR Iran, P.O. Box 37515-374.
Ramin Amini
Islamic Azad University, Shahr-e-Qods Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA comparison of oral/inhaled opium addicts with a healthy control group was investigated. Using the graphite furnace atomic absorption spectroscopy (GF-AAS) followed by chemometric analysis, sub-to-low µg L-1 concentrations of blood lead level (BLL) was detected in both the addict and the control groups. MATERIALS AND

methodsIn this study, BLL of 78 subjects (Iranian volunteers) in two opium-addicted (patient group) and healthy control groups was evaluated. All the volunteers were men. The patient group was comprised of 39 patients who used opium orally or by inhalation with a mean age of 48.6 ± 7.3 years. The patient group was selected through systematic incidental sampling from 150 orally or by inhalation opium-addicted patients referred to Shariati Hospital located in Tehran .The control group (39 subjects) was matched with the patient group with regard to age and sex and with a mean age of 44.8 ± 5.6 years.

resultsThe mean concentration of lead was found to be significantly lower (P = 0.0001) in control group (16.70 ± 12.51 μg/dL) compared to addicts (57.04 ± 46.03 μg/dL). When the addicts were divided into various age groups, there appeared to be a significant difference (p= 0.0451) in blood lead concentration as a function of age, however when the control group was considered, no difference was observed (P = 0.51). Also, a tendency (P = 0.048) towards increasing BLL with respect to BMI was observed due to drug consumption, but there was no significant variation between BLL concentration and BMI when the control group was considered (P = 0.35).

conclusionsIt was observed that the BLL in opium-addicts was significantly higher than that of the healthy control group. The mean difference of both groups was statistically significant.

Indexed as

BloodChemo Metric AnalysisLeadOpium

Identifiers

PMID23105986
PMCPMC3470844
OpenAlexW2183014743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.