ArticleIndian journal of clinical biochemistry : IJCB2010
hs-CRP: A potential marker for hypertension in Kashmiri population.
Article in Indian journal of clinical biochemistry : IJCB, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 55 citations in OpenAlex.
- Association of ideal cardiovascular metrics and serum high-sensitivity C-reactive protein in hypertensive population.PloS one · 2013Trial
- Effects of Spirulina Supplementation on C-Reactive Protein (CRP): A Systematic Review and Dose-Response Meta-Analysis.Food science & nutrition · 2025Review
- C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians.Diseases (Basel, Switzerland) · 2023Review
- Association of hypertension with infection and inflammation in a setting of disadvantage in rural India.Journal of human hypertension · 2022Article
- C-reactive protein in adult Samoans: Population variation and physiological correlates.American journal of human biology : the official journal of the Human Biology Council · 2022Article
- Effect of garlic powder supplementation on blood pressure and hs-C-reactive protein among nonalcoholic fatty liver disease patients: A randomized, double-blind, placebo-controlled trial.Food science & nutrition · 2021Article
- Effect ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies.The British journal of dermatology · 2020Review
- Relationship between high-sensitivity C reactive protein and the risk of gallstone disease: results from the Kailuan cohort study.BMJ open · 2020Article
- Association of serum 25-hydroxyvitamin D levels with primary hypertension: a study from south India.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- A cross-sectional study on serum high-sensitivity C-reactive protein level and shift work among reproductive age women.Caspian journal of internal medicine · 2019Article
- The association between inflammation, obesity and elevated blood pressure in 16-25-year-old females.Journal of human hypertension · 2017Article
- Distribution of High-Sensitivity C-Reactive Protein and Its Relationship with Other Cardiovascular Risk Factors in the Middle-Aged Chinese Population.International journal of environmental research and public health · 2016Article
- The combination of abdominal obesity and high-sensitivity C-reactive protein predicts new-onset hypertension in the general Japanese population: the Tanno-Sobetsu study.Hypertension research : official journal of the Japanese Society of Hypertension · 2015Article
- Correlation Between Hypertension, C-Reactive Protein and Serum Uric Acid With Psychological Well-being.Iranian Red Crescent medical journal · 2014Article
- High sensitivity C-reactive protein concentrations, birthweight and cardiovascular risk markers in Brazilian children.European journal of clinical nutrition · 2013Article
- The Correlation between High-Sensitivity C-Reactive Protein, Matrix Metallopeptidase 9, and Traditional Chinese Medicine Syndrome in Patients with Hypertension.Evidence-based complementary and alternative medicine : eCAM · 2013Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension is the most important public health problem in developing countries and one of the major risk factors for cardiovascular diseases, and it has been reported that hypertension is in part an inflammatory disorder and several workers have reported elevated levels of CRP in hypertensive individuals. The main aim of the present study was to evaluate the association between blood pressure and serum CRP levels across the range of blood pressure categories including prehypertension. A total of 104 patients and 63 control subjects were included in the present study. The level of CRP in the serum samples was estimated by a high sensitivity immunoturbidometric assay. Standard unpaired student's 't' test was used for comparison of hs-CRP levels between hypertensive patients and normotensive control subjects and between patient groups with different grades of hypertension and different durations of hypertensive histories. The mean serum hs-CRP level in hypertensive patients was 3.26 mg/L compared with 1.36 mg/L among normotensive control subjects (P<0.001). On comparison with normotensive control subjects, the hs-CRP levels vary significantly both with grades and duration of hypertension, with most significant difference found in patients with prehypertension (P<0.001), followed by Stage-I (P=0.01) and Stage-II(P=0.02) hypertensives. Significant difference in hs-CRP levels was also found in patients with shorter duration of hypertensive history (≤ 1year) when compared with those with ≥5 years of hypertensive history (P<0.01). Our study reveals a graded association between blood pressure and CRP elevation in people with hypertension. Individuals with prehypertension or with shorter duration of hypertension (≤1 Year) had significantly a greater likelihood of CRP elevation in comparison to chronic stage-I or stage-II hypertensives.
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