Evidence map›Paper›PMID 23105866›Full record

ArticleIndian journal of clinical biochemistry : IJCB2009

Circulating levels of cell adhesion molecules in hypertension.

Kavita K Shalia, Manoj R Mashru, Jagdish B Vasvani, Rajashree A Mokal, Shilpa M Mithbawkar, Priti K Thakur

Open access · greenAbstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Marine drugs · 2018
    Trial
  2. Trial
  3. Article
  4. Review
  5. Irregularities of Coagulation in Hypertension.Current hypertension reports · 2023
    Review
  6. Article
  7. Emerging Anti-Atherosclerotic Therapies.International journal of molecular sciences · 2021
    Review
  8. Current Status of Primary, Secondary, and Tertiary Prevention of Coronary Artery Disease.The International journal of angiology : official publication of the International College of Angiology, Inc · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Pathophysiology and Medical Treatment of Carotid Artery Stenosis.The International journal of angiology : official publication of the International College of Angiology, Inc · 2015
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kavita K ShaliaSir H. N. Medical Research Society, Sir H. N. Hospital and Research Centre, Raja Rammohan Roy Road, Mumbai, 400 004 India.
Manoj R Mashru
Jagdish B Vasvani
Rajashree A Mokal
Shilpa M Mithbawkar
Priti K Thakur
Sir H.N. Reliance Foundation Hospital and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension causes complications such as coronary atherosclerosis and thrombosis wherein inflammatory factors play significant role. In the present study inflammatory molecules such as cell adhesion molecules (CAMs); endothelial (E)-selectin, platelet (P)-selectin, intercellular CAM-1 (ICAM-1), vascular CAM-1 (VCAM-1) and platelet endothelial CAM-1 (PECAM-1) were analysed in subjects newly diagnosed with hypertension with no secondary cause against normotensive healthy individuals. In each group 57 subjects were recruited and soluble (s) levels of CAMs were analysed by ELISA. As compared to controls median of sE-selectin (49.2%, P=0.001), sP-selectin (54.3%, P=0.001), and sICAM-1 (18.9%, P=0.012) were significantly elevated in hypertensive subjects. Significant negative correlation was observed of sP-selectin (spearman rank correlation coefficient (rs) =-0.345, p=0.027) and sPECAM-1 (rs =-0.446, p=0.003) with age in hypertension group. Hypertension may increase expression of certain CAMs while younger hypertensives in addition are also at increased risk of atherothrombosis.

Indexed as

Cell adhesion moleculesHypertensionICAM-1PECAM-1SelectinsVCAM-1

Identifiers

PMID23105866
PMCPMC3453057
OpenAlexW2071060785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.