Evidence map›Paper›PMID 23104919›Full record

ReviewEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2012

Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones.

Natalia A Trayanova, Thomas O'Hara, Jason D Bayer, Patrick M Boyle, Kathleen S McDowell, Jason Constantino, Hermenegild J Arevalo, Yuxuan Hu, Fijoy Vadakkumpadan

Open access · greenAbstract readReview
In one paragraph

Review in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. NHLBI support of systems biology.Frontiers in physiology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Natalia A TrayanovaDepartment of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21218, USA. ntrayanova@jhu.edu
Thomas O'Hara
Jason D Bayer
Patrick M Boyle
Kathleen S McDowell
Jason Constantino
Hermenegild J Arevalo
Yuxuan Hu
Fijoy Vadakkumpadan
Johns Hopkins University · US

Funding

Redox Modification of the Arrhythmic Substrate in Heart FailureR01HL105216 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI O'ROURKE, BRIAN, TRAYANOVA, NATALIA A. · 2011 to 2014
$3.0M
Resynchronizing the Failing Heart: Insights from a Multiscale Cardiac ModelR01HL103428 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TRAYANOVA, NATALIA A. · 2011 to 2014
$2.3M
Image-based models that predict arrhythmia morphology in post-infarction heartsF31HL099275 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI AREVALO, HERMENEGILD JAVIER · 2010 to 2012
$125k
Image-based models of electromechanics in normal and failing heartsF31HL103090 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CONSTANTINO, JASON LANCE · 2010 to 2012
$125k
NHLBI NIH HHS HL099275NHLBI NIH HHS HL103090NHLBI NIH HHS HL103428NHLBI NIH HHS R01 HL103428NHLBI NIH HHS R01 HL105216
6 · The paper itself

Abstract

This article reviews the latest developments in computational cardiology. It focuses on the contribution of cardiac modelling to the development of new therapies as well as the advancement of existing ones for cardiac arrhythmias and pump dysfunction. Reviewed are cardiac modelling efforts aimed at advancing and optimizing existent therapies for cardiac disease (defibrillation, ablation of ventricular tachycardia, and cardiac resynchronization therapy) and at suggesting novel treatments, including novel molecular targets, as well as efforts to use cardiac models in stratification of patients likely to benefit from a given therapy, and the use of models in diagnostic procedures.

Indexed as

ForecastingModels, CardiovascularAnimalsArrhythmias, CardiacCardiologyComputational BiologyComputer SimulationHumansTherapy, Computer-Assisted

Identifiers

PMID23104919
PMCPMC3482619
OpenAlexW2054189242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.