Evidence map›Paper›PMID 23104749›Full record

ArticleInternational journal of STD & AIDS2012

Anticipated changes in sexual risk behaviour following vaccination with a low-efficacy HIV vaccine: survey results from a South African township.

K M Andersson, E Vardas, L M Niccolai, R M Van Niekerk, M M Mogale, I M Holdsworth, M Bogoshi, J A McIntyre, G E Gray

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

K M AnderssonDepartment of Epidemiology & Public Health, Division of Health Policy & Administration, Yale University School of Medicine, 60 College Street, New Haven, CT 06510, USA. kyeen@aya.yale.edu
E Vardas
L M Niccolai
R M Van Niekerk
M M Mogale
I M Holdsworth
M Bogoshi
J A McIntyre
G E Gray

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Making Better Decisions: Policy Modeling for AIDS and Drug AbuseR01DA015612 · NIDA · STANFORD UNIVERSITY · PI OWENS, DOUGLAS K · 2002 to 2017
$9.4M
Yale Training Program in Health Services ResearchT32HS017589 · AHRQ · YALE UNIVERSITY · PI SCHLESINGER, MARK J · 2008 to 2024
$5.6M
AHRQ HHS T32 HS017589AHRQ HHS T32HS017589NIDA NIH HHS R01 DA015612NIDA NIH HHS R01DA015612NIGMS NIH HHS GM07205NIGMS NIH HHS T32 GM007205
6 · The paper itself

Abstract

We assessed the potential for anticipated changes in sexual risk-taking behaviour following hypothetical administration of a low-efficacy preventive HIV vaccine. We developed a survey and collected self-reported data from 158 HIV-negative volunteers in a cohort undergoing prescreening for Phase I/II HIV vaccine trials in Soweto. Overall, 22% reported they might use condoms less frequently; 9% reported that they might increase their frequency of sex with casual/anonymous partners; and 55% reported their sexual partners might want to use condoms less frequently knowing they were vaccinated. Multivariate analyses revealed that anticipated decrease in condom use was predicted by poor comprehension and by young age. Individuals may increase their risk-taking behaviour knowing that a vaccine would provide only incomplete protection against HIV transmission. In HIV vaccine trials and future vaccination programmes, education and risk-reduction counselling will be needed for vaccinated individuals and their partners, and mass media education campaigns may be necessary.

Indexed as

AdolescentAdultAIDS VaccinesAnalysis of VarianceClinical Trials as TopicCohort StudiesCondomsFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansLogistic ModelsMaleMiddle AgedRisk-TakingSouth AfricaAIDS Vaccines

Identifiers

PMID23104749
PMCPMC3699204

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.