Evidence map›Paper›PMID 23104379›Full record

ArticleNucleic acids research2013

Glycan fragment database: a database of PDB-based glycan 3D structures.

Sunhwan Jo, Wonpil Im

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. International journal of molecular sciences · 2022
    Article
  4. Article
  5. Article
  6. Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Article
  8. Three-Dimensional Structures of Carbohydrates and Where to Find Them.International journal of molecular sciences · 2020
    Review
  9. Article
  10. GlyMDB: Glycan Microarray Database and analysis toolset.Bioinformatics (Oxford, England) · 2020
    Article
  11. Current research in structural biology · 2020
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Modeling of Oligosaccharides within Glycoproteins from Free-Energy Landscapes.Journal of chemical information and modeling · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sunhwan JoDepartment of Molecular Biosciences and Center for Bioinformatics, The University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA.
Wonpil Im
University of Kansas · US

Funding

TRAFFICKING OF THE PLASMA MEMBRANE CA2+-ATPASE TO RAFTSP20RR017708 · NCRR · UNIVERSITY OF KANSAS LAWRENCE · PI ANBANANDAM, ASOKAN · 2002 to 2011
$20.1M
Protein Structure and FunctionP20GM103420 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HANZLIK, ROBERT P · 2012 to 2012
$2.0M
NCRR NIH HHS P20 RR017708NIGMS NIH HHS P20 GM103420
6 · The paper itself

Abstract

The glycan fragment database (GFDB), freely available at http://www.glycanstructure.org, is a database of the glycosidic torsion angles derived from the glycan structures in the Protein Data Bank (PDB). Analogous to protein structure, the structure of an oligosaccharide chain in a glycoprotein, referred to as a glycan, can be characterized by the torsion angles of glycosidic linkages between relatively rigid carbohydrate monomeric units. Knowledge of accessible conformations of biologically relevant glycans is essential in understanding their biological roles. The GFDB provides an intuitive glycan sequence search tool that allows the user to search complex glycan structures. After a glycan search is complete, each glycosidic torsion angle distribution is displayed in terms of the exact match and the fragment match. The exact match results are from the PDB entries that contain the glycan sequence identical to the query sequence. The fragment match results are from the entries with the glycan sequence whose substructure (fragment) or entire sequence is matched to the query sequence, such that the fragment results implicitly include the influences from the nearby carbohydrate residues. In addition, clustering analysis based on the torsion angle distribution can be performed to obtain the representative structures among the searched glycan structures.

Indexed as

Databases, ChemicalCarbohydrate ConformationCluster AnalysisDatabases, ProteinGlycoproteinsInternetPolysaccharidesUser-Computer InterfaceGlycoproteinsPolysaccharides

Identifiers

PMID23104379
PMCPMC3531216
OpenAlexW2002755970

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.