Trial reportNature neuroscience2012
A supramodal accumulation-to-bound signal that determines perceptual decisions in humans.
Trial report in Nature neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 331 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
331 citing papers in PubMed.
- EEG reveals that dextroamphetamine improves cognitive control through multiple processes in healthy participants.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Trial
- Premature commitment to uncertain decisions during human NMDA receptor hypofunction.Nature communications · 2022Trial
- Cortical beta power reflects decision dynamics and uncovers multiple facets of post-error adaptation.Nature communications · 2018Trial
- Combined eye tracking and electroencephalography during referential selection in dyadic interaction.Behavior research methods · 2026Article
- Evidence for early and late prediction error-associated ERP responses during probabilistic cueing.iScience · 2026Article
- Assessing the effect of subthalamic stimulation on metaperception in obsessive-compulsive disorder.Translational psychiatry · 2026Article
- Song Familiarity Relies on Evidence Accumulation.Psychophysiology · 2026Article
- Perceptual decision-making in the sound-induced flash illusion: a trial-level hierarchical Bayesian integration of EEG and behavior.Behavioral and brain functions : BBF · 2026Article
- Neurophysiological Differentiation of Conversion to Alzheimer's Disease: Longitudinal Changes in P300 Amplitude as an Indicator of Mild Cognitive Impairment Progression.Brain and behavior · 2026Article
- Neurophysiology of Sleep-Deprivation Part 1: Effects of Sleep-Deprivation on Event-Related Potentials (ERPs)-Systematic and Mechanistic Review.Journal of clinical medicine · 2026Review
- Combining EEG signals from the 2 members of a team to improve event identification.Neuroimage. Reports · 2026Article
- Ethical Decision-Making in Chilean University Students: Behavioral and Electroencephalographic Evidence from Professional Ethical Dilemmas.Behavioral sciences (Basel, Switzerland) · 2026Article
- Article
- Trial-level sequence modeling reveals hidden dynamics of dual-task interference.PLoS computational biology · 2026Article
- Article
- Sex differences in event-related potentials and their clinical predictive value in first-episode antipsychotic-naïve schizophrenia.European archives of psychiatry and clinical neuroscience · 2026Article
- Readout and delayed transmission of initial afferent V1 activity in decisions about stimulus contrast.eLife · 2026Article
- A Shared Theta-Rhythmic Process for Selective Sampling of Environmental Information and Internally Stored Information.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- A Movement-Independent Signature of Urgency during Human Perceptual Decision-Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Phasic and tonic arousal distinctly shape human decision bias.Communications biology · 2026Article
271 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In theoretical accounts of perceptual decision-making, a decision variable integrates noisy sensory evidence and determines action through a boundary-crossing criterion. Signals bearing these very properties have been characterized in single neurons in monkeys, but have yet to be directly identified in humans. Using a gradual target detection task, we isolated a freely evolving decision variable signal in human subjects that exhibited every aspect of the dynamics observed in its single-neuron counterparts. This signal could be continuously tracked in parallel with fully dissociable sensory encoding and motor preparation signals, and could be systematically perturbed mid-flight during decision formation. Furthermore, we found that the signal was completely domain general: it exhibited the same decision-predictive dynamics regardless of sensory modality and stimulus features and tracked cumulative evidence even in the absence of overt action. These findings provide a uniquely clear view on the neural determinants of simple perceptual decisions in humans.
Indexed as
Identifiers
23103963What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.