Evidence map›Paper›PMID 23103764›Full record

ArticleThe EMBO journal2012

Nucleosome positioning and transcription: fission yeast CHD remodellers make their move.

Leila Touat-Todeschini, Edwige Hiriart, André Verdel

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The EMBO journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Leila Touat-TodeschiniINSERM, U823, Université Joseph Fourier - Grenoble 1, Institut Albert Bonniot, Faculté de Médecine, La Tronche Cedex, France.
Edwige Hiriart
André Verdel
Institut pour l'avancée des biosciences · FRUniversité Joseph Fourier · FR

Funding

European Research Council 210896
6 · The paper itself

Abstract

Regularly positioned nucleosomes are a common feature of 5' ends of most eukaryotic genes. A series of three studies, Shim et al (2012) and Pointner et al (2012) in this issue of The EMBO Journal and Hennig et al (2012) in EMBO Reports, now show that in the fission yeast Schizosaccharomyces pombe this intragenic nucleosome positioning mostly requires two ATP-dependent remodellers of the CHD family, Hrp1 and Hrp3. Moreover, they suggest that Hrp1- and Hrp3-dependent nucleosome spacing contributes to the silencing of cryptic antisense transcription.

Indexed as

Gene Expression Regulation, FungalAdenosine TriphosphatasesAdenosine TriphosphateDNA-Binding ProteinsDNA HelicasesEuchromatinHeterochromatinNucleosomesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsAdenosine TriphosphatasesAdenosine TriphosphateCHD1 protein, S cerevisiaeDNA-Binding ProteinsDNA HelicasesEuchromatinHeterochromatinhrp1 protein, S pombeHrp3 protein, S pombeNucleosomesSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe Proteins

Identifiers

PMID23103764
PMCPMC3512389
OpenAlexW2155840145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.