ArticleEpilepsy & behavior : E&B2012
Effect of lateralized temporal lobe epilepsy on the default mode network.
Article in Epilepsy & behavior : E&B, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
75 citing papers in PubMed, 3 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Voxel-wise Functional Connectivity of the Default Mode Network in Epilepsies: A Systematic Review and Meta-Analysis.Current neuropharmacology · 2022Pooled it
- Functional connectivity of hippocampus in temporal lobe epilepsy depends on hippocampal dominance: a systematic review of the literature.Journal of neurology · 2022Pooled it
- Verbal fluency in focal epilepsy: a systematic review and meta-analysis.Neuropsychology review · 2014Pooled it
- Interpretable Multiscale Directed Temporal Graph Learning for MEG-Based Identification and Lateralization of Temporal Lobe Epilepsy.Sensors (Basel, Switzerland) · 2026Article
- Thalamic connectivity mirrors spatial maps of network dysfunction in nonlesional focal epilepsy.Epilepsia · 2026Article
- Dynamic Analysis of Gray Matter and White Matter Functional Network Connectivity in Individuals with Temporal Lobe Epilepsy.Research square · 2026Article
- Convergent functional networks of intrinsic activity alterations in temporal lobe epilepsy and their molecular correlates.Frontiers in molecular neuroscience · 2026Article
- Seizure-onset zone lateralization in temporal lobe epilepsy using 7T rs-fMRI: Direct comparison with 3T rs-fMRI.Epilepsia · 2025Article
- Motor and default mode network states of rest in frontal lobe epilepsy.Neuroimage. Reports · 2025Article
- Transcriptionally downregulated GABAergic genes associated with synaptic density network dysfunction in temporal lobe epilepsy.European journal of nuclear medicine and molecular imaging · 2025Article
- Intrinsic brain network stability during kainic acid-induced epileptogenesis.Epilepsia open · 2025Article
- Aberrant white matter and subcortical gray matter functional network connectivity associated with static and dynamic characteristics in subjects with temporal lobe epilepsy.Frontiers in neuroscience · 2025Article
- Brain Networks for Cortical Atrophy and Responsive Neurostimulation in Temporal Lobe Epilepsy.JAMA neurology · 2024Article
- Altered correlation of concurrently recorded EEG-fMRI connectomes in temporal lobe epilepsy.Network neuroscience (Cambridge, Mass.) · 2024Article
- Lateralization of delta band power in magnetoencephalography (MEG) in patients with unilateral focal epilepsy and its relation to verbal fluency.Brain and behavior · 2023Article
- Abnormal brain functional network dynamics in sleep-related hypermotor epilepsy.CNS neuroscience & therapeutics · 2023Article
- Subcortical Functional Connectivity Gradients in Temporal Lobe Epilepsy.medRxiv : the preprint server for health sciences · 2023Article
- Abnormal metabolic connectivity in default mode network of right temporal lobe epilepsy.Frontiers in neuroscience · 2023Article
- Characterization of resting functional MRI activity alterations across epileptic foci and networks.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Network analysis of preictal iEEG reveals changes in network structure preceding seizure onset.Scientific reports · 2022Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The default mode network (DMN) is composed of cerebral regions involved in conscious, resting state cognition. The hippocampus is an essential component of this network. Here, the DMN in TLE is compared to control subjects to better understand its involvement in TLE. We performed resting state connectivity analysis using regions of interest (ROIs) in the retrosplenium/precuneus (Rsp/PCUN) and the ventro-medial pre-frontal cortex (vmPFC) in 36 subjects (11 with right TLE, 12 with left TLE, 13 controls) to delineate the posterior and anterior DMN regions respectively. We found reduced connectivity of the posterior to the anterior DMN in patients with both right and left TLE. However, the posterior and anterior networks were found to be individually preserved. Lateralization of TLE affects the DMN with left TLE demonstrating more extensive networks. These DMN changes may be relevant to altered cognition and memory in TLE and may be relevant to right vs. left TLE differences in cognitive involvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.