Evidence map›Paper›PMID 23102628›Full record

ArticleJournal of psychiatric research2013

Lifetime history of traumatic events in an American Indian community sample: heritability and relation to substance dependence, affective disorder, conduct disorder and PTSD.

Cindy L Ehlers, Ian R Gizer, David A Gilder, Rachael Yehuda

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

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  11. Trends and disparities in American Indian/Alaska Native unintentional injury mortality from 1999 to 2016.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Cindy L EhlersMolecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA. cindye@scripps.edu
Ian R Gizer
David A Gilder
Rachael Yehuda
Scripps Research Institute · USJames J. Peters VA Medical Center · USUniversity of Missouri · US

Funding

Deep sequencing studies for cannabis and stimulant dependenceR01DA030976 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EHLERS, CINDY L, GELERNTER, JOEL · 2010 to 2014
$16.5M
RISK FACTORS FOR ALCOHOLISM IN NATIVE AMERICANSR37AA010201 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI EHLERS, CINDY L · 2007 to 2015
$7.0M
RISK FACTORS FOR ALCOHOLISM IN NATIVE AMERICANSR01AA010201 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI EHLERS, CINDY L · 1994 to 2006
$3.8M
NIAAA NIH HHS 5R37 AA010201NIAAA NIH HHS R01 AA010201NIAAA NIH HHS R37 AA010201NIDA NIH HHS DA030976NIDA NIH HHS R01 DA030976
6 · The paper itself

Abstract

American Indians appear to experience a higher rate of traumatic events than what has been reported in general population surveys. American Indians also suffer higher alcohol related death rates than any other ethnic group in the U.S. population. Therefore efforts to delineate factors which may uniquely contribute to increased likelihood of trauma, post traumatic stress disorder (PTSD), and substance use disorders (SUD) over the lifetime in American Indians are important because of the high burden of morbidity and mortality that they pose to American Indian communities. Participants were American Indians recruited from reservations that were assessed with the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA), family history assessment and the stressful-life-events scale. Of the 309 participants, equivalent numbers of men and women (94%) reported experiencing traumas; however, a larger proportion of women received a PTSD diagnosis (38%) than men (29%). Having experienced multiple trauma and sexual abuse were most highly associated with PTSD. Having experienced assaultive trauma and having PTSD symptoms were both found to be moderately heritable (30-50%). Logistic regression revealed that having an anxiety and/or affective disorder and having a substance dependent diagnosis, but not having antisocial personality disorder/conduct disorder, were significantly correlated with having a diagnosis of PTSD. These studies suggest that trauma is highly prevalent in this American Indian community, it is heritable, is associated with PTSD, affective/anxiety disorders and substance dependence. Additionally, trauma, PTSD and substance dependence appear to all co-emerge in early adulthood in this high-risk population.

Indexed as

Indians, North AmericanAdolescentAdultConduct DisorderFemaleHumansMaleMiddle AgedMood DisordersPsychiatric Status Rating ScalesResidence CharacteristicsStress Disorders, Post-TraumaticSubstance-Related DisordersYoung Adult

Identifiers

PMID23102628
PMCPMC3530021
OpenAlexW2153714536

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.