ArticleBMJ open2012
Ankle-Brachial Index determination and peripheral arterial disease diagnosis by an oscillometric blood pressure device in primary care: validation and diagnostic accuracy study.
Article in BMJ open, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 41 citations in OpenAlex.
- Deep-learning-based diagnostic models for transcutaneous oxygen pressure-defined peripheral arterial disease and lower extremity wound healing in patients with diabetic foot.BMC medical informatics and decision making · 2026Article
- Identifying Risk Factors for Lower Extremity Artery Disease (LEAD) in Cardiology Patients: The Role of Ankle-Brachial Index Measurement.Journal of clinical medicine · 2024Article
- Peripheral artery disease diagnosis based on deep learning-enabled analysis of non-invasive arterial pulse waveforms.Computers in biology and medicine · 2024Article
- Automated Measurements of Ankle-Brachial Index: A Narrative Review.Journal of clinical medicine · 2021Review
- Deep Learning-Based Diagnosis of Peripheral Artery Disease via Continuous Property-Adversarial Regularization: Preliminary in Silico Study.IEEE access : practical innovations, open solutions · 2021Article
- Asia-Pacific Consensus Statement on the Management of Peripheral Artery Disease: A Report from the Asian Pacific Society of Atherosclerosis and Vascular Disease Asia-Pacific Peripheral Artery Disease Consensus Statement Project Committee.Journal of atherosclerosis and thrombosis · 2020Article
- Detection and Severity Assessment of Peripheral Occlusive Artery Disease via Deep Learning Analysis of Arterial Pulse Waveforms: Proof-of-Concept and Potential Challenges.Frontiers in bioengineering and biotechnology · 2020Article
- Validity and reliability of the ankle-brachial index by oscillometric blood pressure and automated ankle-brachial index.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Automated plethysmographic measurement of the ankle-brachial index: a comparison with the doppler ultrasound method.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
- Different methods of calculating ankle-brachial index in mid-elderly men and women: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2016Article
- Evaluation of 6- and 12-month supervised exercise training on strength and endurance parameters in patients with peripheral arterial disease.Wiener klinische Wochenschrift · 2014Article
- Current utility of the ankle-brachial index (ABI) in general practice: implications for its use in cardiovascular disease screening.BMC family practice · 2014Article
- Digital ankle-brachial index technology used in primary care settings to detect flow obstruction: a population based registry study.BMC research notes · 2013Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the level of agreement between a 'conventional' Ankle-Brachial Index (ABI) measurement (using Doppler and mercury sphygmomanometer taken by a research nurse) and a 'pragmatic' ABI measure (using an oscillometric device taken by a practice nurse) in primary care. To ascertain the utility of a pragmatic ABI measure for the diagnosis of peripheral arterial disease (PAD) in primary care.
designCross-sectional validation and diagnostic accuracy study. Descriptive analyses were used to investigate the agreement between the two procedures using the Bland and Altman method to determine whether the correlation between ABI readings varied systematically. Diagnostic accuracy was assessed via sensitivity, specificity, accuracy, likelihood ratios, positive and negative predictive values, with ABI readings dichotomised and Receiver Operating Curve analysis using both univariable and multivariable logistic regression.
settingPrimary care in metropolitan and rural Victoria, Australia between October 2009 and November 2010.
participants250 persons with cardiovascular disease (CVD) or at high risk (three or more risk factors) of CVD.
resultsDespite a strong association between the two method's measurements of ABI there was poor agreement with 95% of readings within ±0.4 of the 0.9 ABI cut point. The multivariable C statistic of diagnosis of PAD was 0.89. Other diagnostic measures were sensitivity 62%, specificity 92%, positive predictive value 67%, negative predictive value 90%, accuracy 85%, positive likelihood ratio 7.3 and the negative likelihood ratio 0.42.
conclusionsOscillometric ABI measures by primary care nurses on a population with a 22% prevalence of PAD lacked sufficient agreement with conventional measures to be recommended for routine diagnosis of PAD. This pragmatic method may however be used as a screening tool high-risk and overt CVD patients in primary care as it can reliably exclude the condition.
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