Evidence map›Paper›PMID 23100245›Full record

ArticleAmerican journal of epidemiology2012

Modeling the salivary cortisol profile in population research: the multi-ethnic study of atherosclerosis.

Brisa N Sánchez, Meihua Wu, Trivellore E Raghunathan, Ana V Diez-Roux

Abstract read
In one paragraph

Article in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Salivary cortisol and α-amylase: subclinical indicators of stress as cardiometabolic risk.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brisa N SánchezDepartment of Biostatistics, University of Michigan School of Public Health, 1415 Washington Heights, Rm 4164, Ann Arbor, MI 48109, USA. brisa@umich.edu
Meihua Wu
Trivellore E Raghunathan
Ana V Diez-Roux

Funding

Stress, Gene-Environment Interaction and Cardiovascular DiseaseR01HL101161 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIEZ ROUX, ANA VICTORIA, NEEDHAM, BELINDA L. · 2010 to 2013
$4.1M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
Tools for Measuring and Analyzing Cortisol Levels in Population Studies of HealthR21DA024273 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIEZ ROUX, ANA VICTORIA · 2007 to 2010
$1.2M
SUBCLINICAL CARDIOVASCULAR DISEASE COORDINATING CENTER-N01HC95159-268095159N01HC095159 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 1999 to 2006
$304k
Adjunctive Use of Apyrase to Fibrinolytic TherapyR43HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2009 to 2009
$226k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READINGN01HC095169 · HC · LA BIOMED RES INST/ HARBOR UCLA MED CTR · PI DETRANO, ROBERT · 1999 to 2001
$124k
NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095169NHLBI NIH HHS N01-HC-95159NHLBI NIH HHS N01-HC-95169NIDA NIH HHS R21 DA024273
6 · The paper itself

Abstract

In many studies, it has been hypothesized that stress and its biologic consequences may contribute to disparities in rates of cardiovascular disease. However, understanding of the most appropriate statistical methods to analyze biologic markers of stress, such as salivary cortisol, remains limited. The authors explore the utility of various statistical methods in modeling daily cortisol profiles in population-based studies. They demonstrate that the proposed methods allow additional insight into the cortisol profile compared with commonly used summaries of the profiles based on raw data. For instance, one can gain insights regarding the shape of the population average curve, characterize the types of individual-level departures from the average curve, and better understand the relation between covariates and attained cortisol levels or slopes at various points of the day, in addition to drawing inferences regarding common features of the cortisol profile, such as the cortisol awakening response and the area under the curve. The authors compare the inference and interpretations drawn from these methods and use data collected as part of the Multi-Ethnic Study of Atherosclerosis to illustrate them.

Indexed as

Models, StatisticalAgedAge FactorsAtherosclerosisEthnicityFemaleHumansHydrocortisoneMaleMiddle AgedSalivaSex FactorsStress, PsychologicalHydrocortisone

Identifiers

PMID23100245
PMCPMC3626059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.