ArticleJournal of neurophysiology2013
Effects of cortical feedback on the spatial properties of relay cells in the lateral geniculate nucleus.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Dual parallel stream-specific and generalized effects of corticogeniculate feedback on LGN neurons in primate and carnivore.Nature communications · 2025Article
- Cortical feedback modulates distinct critical period development in mouse visual thalamus.iScience · 2023Article
- Robust effects of corticothalamic feedback and behavioral state on movie responses in mouse dLGN.eLife · 2022Article
- Role of Feedback Connections in Central Visual Processing.Annual review of vision science · 2020Review
- Context-dependent and dynamic functional influence of corticothalamic pathways to first- and higher-order visual thalamus.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Morphological heterogeneity among corticogeniculate neurons in ferrets: quantification and comparison with a previous report in macaque monkeys.The Journal of comparative neurology · 2019Article
- Firing-rate based network modeling of the dLGN circuit: Effects of cortical feedback on spatiotemporal response properties of relay cells.PLoS computational biology · 2018Article
- Biophysical network modeling of the dLGN circuit: Effects of cortical feedback on spatial response properties of relay cells.PLoS computational biology · 2018Article
- Orientation Tuning of Correlated Activity in the Developing Lateral Geniculate Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Presynaptic Neuronal Nicotinic Receptors Differentially Shape Select Inputs to Auditory Thalamus and Are Negatively Impacted by Aging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Corticogeniculate feedback sharpens the temporal precision and spatial resolution of visual signals in the ferret.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- A Role for Auditory Corticothalamic Feedback in the Perception of Complex Sounds.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Retinal and Nonretinal Contributions to Extraclassical Surround Suppression in the Lateral Geniculate Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- A cross-species comparison of corticogeniculate structure and function.Visual neuroscience · 2017Article
- Cortex dynamically modulates responses of thalamic relay neurons through prolonged circuit-level disinhibition in rat thalamus in vivo.Journal of neurophysiology · 2016Article
- Allostatic Self-efficacy: A Metacognitive Theory of Dyshomeostasis-Induced Fatigue and Depression.Frontiers in human neuroscience · 2016Article
- Visual Functions of the Thalamus.Annual review of vision science · 2015Article
- Complex Effects on In Vivo Visual Responses by Specific Projections from Mouse Cortical Layer 6 to Dorsal Lateral Geniculate Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Surround suppression and temporal processing of visual signals.Journal of neurophysiology · 2015Article
- Microcircuits and their interactions in epilepsy: is the focus out of focus?Nature neuroscience · 2015Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Feedback connections to early-level sensory neurons have been shown to affect many characteristics of their neural response. Because selectivity for stimulus size is a fundamental property of visual neurons, we examined the summation tuning and discretely mapped receptive field (RF) properties of cells in the lateral geniculate nucleus (LGN) both with and without feedback from visual cortex. Using extracellular recording in halothane-anesthetized cats, we used small luminance probes displaced in Cartesian coordinates to measure discrete response area, and optimal sinusoidal gratings of varying diameter to estimate preferred optimal summation size and level of center-surround antagonism. In conditions where most cortical feedback was pharmacologically removed, discretely mapped RF response areas showed an overall significant enlargement for the population compared with control conditions. A switch to increased levels of burst firing, spatially displaced from the RF center, suggested this was mediated by changes in excitatory-inhibitory balance across visual space. With the use of coextensive stimulation, there were overall highly significant increases in the optimal summation size and reduction of surround antagonism with removal of cortical feedback in the LGN. When fitted with a difference-of-Gaussian (DOG) model, changes in the center size, center amplitude, and surround amplitude parameters were most significantly related to the removal of cortical feedback. In summary, corticothalamic innervation of the visual thalamus can modify spatial summation properties in LGN relay cells, an effect most parsimoniously explained by changes in the excitatory-inhibitory balance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.