Evidence map›Paper›PMID 23099314›Full record

ReviewExperimental and molecular pathology2012

Host response in tumor diagnosis and prognosis: importance of immunologists and pathologists alliance.

Olivera J Finn

Abstract readReview
In one paragraph

Review in Experimental and molecular pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Olivera J FinnUniversity of Pittsburgh School of Medicine, Pittsburgh, PA 15232, USA. ojfinn@pitt.edu
University of Pittsburgh · US

Funding

T CELL IMMUNITY TO EPITHELIAL TUMOR MUCINSR01CA056103 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINN, OLIVERA J · 1991 to 2013
$3.4M
Dendritic Cell Biology and TherapyR01CA168392 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINN, OLIVERA J · 2011 to 2015
$2.0M
NCI NIH HHS R01 CA056103NCI NIH HHS R01 CA168392
6 · The paper itself

Abstract

Pathologists and immunologists have collaborated over many years in their efforts to understand and properly diagnose cancer. The ability of pathologists to correctly diagnose this disease was facilitated by the development of immunohistology that utilized specificity of antibodies to distinguish between normal cells and cancer cells. Further boost was provided through the advent of monoclonal antibodies. The two disciplines are now together on the brink of a paradigm shift resulting from a better understanding of the importance for cancer diagnosis and prognosis to consider not only the characteristics of the cancer cells, but also the cancer microenvironment reflecting the host response to the disease. This new immunology and pathology alliance named "Immunoscore" will advance research in both disciplines as well as benefit patients.

Indexed as

Allergy and ImmunologyInterprofessional RelationsPathologyReferral and ConsultationAdenocarcinomaBiomarkers, TumorColonic NeoplasmsFemaleHumansLymphocytes, Tumor-InfiltratingMaleMucin-1Patient Care TeamPrognosisTissue Array AnalysisBiomarkers, TumorMUC1 protein, humanMucin-1

Identifiers

PMID23099314
PMCPMC3518699
OpenAlexW1983616486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.