ArticleBioscience reports2012
The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction.
Article in Bioscience reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Consuming a Linoleate-Rich Diet Increases Concentrations of Tetralinoleoyl Cardiolipin in Mouse Liver and Alters Hepatic Mitochondrial Respiration.The Journal of nutrition · 2024Article
- Mitoribosome Biogenesis.Methods in molecular biology (Clifton, N.J.) · 2023Article
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- The distinct spatiotemporal distribution and effect of feed restriction on mtDNA copy number in broilers.Scientific reports · 2020Article
- A framework for examining how diet impacts tumour metabolism.Nature reviews. Cancer · 2019Review
- Article
- Calorie restriction as an intervention in ageing.The Journal of physiology · 2016Review
- The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice.Biogerontology · 2015Review
- The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015Article
- Dietary fat and aging modulate apoptotic signaling in liver of calorie-restricted mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015Article
- Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice.Aging cell · 2014Article
- Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie restricted mice fed with different dietary fats.Experimental gerontology · 2014Article
- Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice.Nature communications · 2014Article
- Dietary fat, fatty acid saturation and mitochondrial bioenergetics.Journal of bioenergetics and biomembranes · 2014Article
- The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction.Physiological research · 2014Article
- Alterations of ultrastructural and fission/fusion markers in hepatocyte mitochondria from mice following calorie restriction with different dietary fats.The journals of gerontology. Series A, Biological sciences and medical sciences · 2013Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
To investigate the role mitochondrial membrane lipids play in the actions of CR (calorie restriction), C57BL/6 mice were assigned to four groups (control and three 40% CR groups) and the CR groups were fed diets containing soya bean oil (also in the control diet), fish oil or lard. The fatty acid composition of the major mitochondrial phospholipid classes, proton leak and H(2)O(2) production were measured in liver mitochondria following 1 month of CR. The results indicate that mitochondrial phospholipid fatty acids reflect the PUFA (polyunsaturated fatty acid) profile of the dietary lipid sources. CR significantly decreased the capacity of ROS (reactive oxygen species) production by Complex III but did not markedly alter proton leak and ETC (electron transport chain) enzyme activities. Within the CR regimens, the CR-fish group had decreased ROS production by both Complexes I and III, and increased proton leak when compared with the other CR groups. The CR-lard group showed the lowest proton leak compared with the other CR groups. The ETC enzyme activity measurements in the CR regimens showed that Complex I activity was decreased in both the CR-fish and CR-lard groups. Moreover, the CR-fish group also had lower Complex II activity compared with the other CR groups. These results indicate that dietary lipid composition does influence liver mitochondrial phospholipid composition, ROS production, proton leak and ETC enzyme activities in CR animals.
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Registered trials
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