ArticleBiomacromolecules2012
Facile functionalization of polyesters through thiol-yne chemistry for the design of degradable, cell-penetrating and gene delivery dual-functional agents.
Article in Biomacromolecules, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 75 citations in OpenAlex.
- Gene Delivery Mediated by Backbone-Degradable RAFT Copolymers.Biomacromolecules · 2026Article
- Four-Dimensional Printing of Shape Memory Polymers for Biomedical Applications: Advances in DLP and SLA Manufacturing.Polymers · 2025Review
- Functional Polyesters: Tailoring Structure and Biomedical Functions.Polymer science & technology (Washington, D.C.) · 2025Review
- Cationic Polymers as Transfection Reagents for Nucleic Acid Delivery.Pharmaceutics · 2023Review
- Article
- Disulfide-yne reaction: controlling the reactivity of a surface by light.RSC advances · 2021Article
- PEGylated Amine-Functionalized Poly(ε-caprolactone) for the Delivery of Plasmid DNA.Materials (Basel, Switzerland) · 2020Article
- Biodegradable Polymers for Gene-Delivery Applications.International journal of nanomedicine · 2020Review
- A Supramolecular Platform for the Introduction of Fc-Fusion Bioactive Proteins on Biomaterial Surfaces.ACS applied polymer materials · 2019Article
- Facile Gene Delivery Derived from Branched Low Molecular Weight Polyethylenimine by High Efficient Chemistry.Journal of biomedical nanotechnology · 2018Article
- Living Ring-Opening Polymerization ofFrontiers in chemistry · 2018Review
- Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes.Journal of visualized experiments : JoVE · 2017Article
- Ionic liquids with thioether motifs as synthetic cationic lipids for gene delivery.Chemical communications (Cambridge, England) · 2017Article
- Biodegradable micelles capable of mannose-mediated targeted drug delivery to cancer cells.Macromolecular rapid communications · 2015Article
- Synthesis and click chemistry of a new class of biodegradable polylactide towards tunable thermo-responsive biomaterials.Polymer chemistry · 2015Article
- Synthesis of a library of propargylated and PEGylated α-hydroxy acids toward "clickable" polylactides via hydrolysis of cyanohydrin derivatives.The Journal of organic chemistry · 2014Article
- Ring-opening polymerization of L-lactic acid O-carboxyanhydrides initiated by alkoxy rare earth compounds.Molecules (Basel, Switzerland) · 2013Article
- Redox-responsive, core-cross-linked micelles capable of on-demand, concurrent drug release and structure disassembly.Biomacromolecules · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Synthesis of polyesters bearing pendant amine groups with controlled molecular weights and narrow molecular weight distributions was achieved through ring-opening polymerization of 5-(4-(prop-2-yn-1-yloxy)benzyl)-1,3-dioxolane-2,4-dione, an O-carboxyanhydride derived from tyrosine, followed by thiol-yne "click" photochemistry with 2-aminoethanethiol hydrochloride. This class of biodegradable polymers displayed excellent cell penetration and gene delivery properties with low toxicities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.