ArticleBiology direct2012
Distinct groups of repetitive families preserved in mammals correspond to different periods of regulatory innovations in vertebrates.
Article in Biology direct, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
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- Exploration of the potential of genomic editing in the treatment of congenital adrenal hyperplasia.Frontiers in endocrinology · 2025Review
- Comparative repeatome analysis reveals new evidence on genome evolution in wild diploid Arachis (Fabaceae) species.Planta · 2022Article
- Repeatome-Based Phylogenetics in Pelargonium Section Ciconium (Sweet) Harvey.Genome biology and evolution · 2021Article
- Simultaneous TE Analysis of 19 Heliconiine Butterflies Yields Novel Insights into Rapid TE-Based Genome Diversification and Multiple SINE Births and Deaths.Genome biology and evolution · 2019Article
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- Horizontal acquisition of transposable elements and viral sequences: patterns and consequences.Current opinion in genetics & development · 2018Review
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- Evolution and Diversity of Transposable Elements in Vertebrate Genomes.Genome biology and evolution · 2017Review
- Friend or Foe: Epigenetic Regulation of Retrotransposons in Mammalian Oogenesis and Early Development.The Yale journal of biology and medicine · 2016Review
- Nothing in Evolution Makes Sense Except in the Light of Genomics: Read-Write Genome Evolution as an Active Biological Process.Biology · 2016Review
- Genomic repeat abundances contain phylogenetic signal.Systematic biology · 2015Article
- A new genome-wide method to track horizontally transferred sequences: application to Drosophila.Genome biology and evolution · 2014Article
- Elaborate security TRAINing to fight against expression of genomic junk.Cell cycle (Georgetown, Tex.) · 2013Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMammalian genomes are repositories of repetitive DNA sequences derived from transposable elements (TEs). Typically, TEs generate multiple, mostly inactive copies of themselves, commonly known as repetitive families or families of repeats. Recently, we proposed that families of TEs originate in small populations by genetic drift and that the origin of small subpopulations from larger populations can be fueled by biological innovations.
resultsWe report three distinct groups of repetitive families preserved in the human genome that expanded and declined during the three previously described periods of regulatory innovations in vertebrate genomes. The first group originated prior to the evolutionary separation of the mammalian and bird lineages and the second one during subsequent diversification of the mammalian lineages prior to the origin of eutherian lineages. The third group of families is primate-specific.
conclusionsThe observed correlation implies a relationship between regulatory innovations and the origin of repetitive families. Consistent with our previous hypothesis, it is proposed that regulatory innovations fueled the origin of new subpopulations in which new repetitive families became fixed by genetic drift.
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