Evidence map›Paper›PMID 23097636›Full record

Trial reportTheScientificWorldJournal2012

Noni juice improves serum lipid profiles and other risk markers in cigarette smokers.

Mian-Ying Wang, Lin Peng, Vicki Weidenbacher-Hoper, Shixin Deng, Gary Anderson, Brett J West

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in TheScientificWorldJournal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. The Effect ofEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  4. Review
  5. Iridoids are natural glycation inhibitors.Glycoconjugate journal · 2016
    Review
  6. Anti-Diabetic Potential of Noni: The Yin and the Yang.Molecules (Basel, Switzerland) · 2015
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mian-Ying WangDepartment of Pathology, University of Illinois College of Medicine at Rockford, 1601 Parkview Avenue, Rockford, IL 61107, USA.
Lin Peng
Vicki Weidenbacher-Hoper
Shixin Deng
Gary Anderson
Brett J West
Illinois College · USUniversity of Illinois Chicago, Rockford campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigarette smoke-induced oxidative stress leads to dyslipidemia and systemic inflammation. Morinda citrifolia (noni) fruit juice has been found previously to have a significant antioxidant activity. One hundred thirty-two adult heavy smokers completed a randomized, double blind, placebo-controlled clinical trial designed to investigate the effect of noni juice on serum cholesterol, triglyceride, low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), high-sensitivity C-reactive protein (hs-CRP), and homocysteine. Volunteers drank noni juice or a fruit juice placebo daily for one month. Drinking 29.5 mL to 188 mL of noni juice per day significantly reduced cholesterol levels, triglycerides, and hs-CRP. Decreases in LDL and homocysteine, as well increases in HDL, were also observed among noni juice drinkers. The placebo, which was devoid of iridoid glycosides, did not significantly influence blood lipid profiles or hs-CRP. Noni juice was able to mitigate cigarette smoke-induced dyslipidemia, an activity associated with the presence of iridoids.

Indexed as

BeveragesPhytotherapySmoking PreventionAdultAntioxidantsCholesterolCholesterol, HDLCholesterol, LDLC-Reactive ProteinDouble-Blind MethodDyslipidemiasFemaleHomocysteineHumansLipidsMaleAntioxidantsCholesterolCholesterol, HDLCholesterol, LDLC-Reactive ProteinHomocysteineLipidsPlant ExtractsTriglycerides

Identifiers

PMID23097636
PMCPMC3477557
OpenAlexW2137220276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.