Evidence map›Paper›PMID 23097454›Full record

ArticleJournal of virology2013

The C-terminal region of Rift Valley fever virus NSm protein targets the protein to the mitochondrial outer membrane and exerts antiapoptotic function.

Kaori Terasaki, Sungyong Won, Shinji Makino

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 58 citations in OpenAlex.

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  19. A Look intoViruses · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kaori TerasakiDepartment of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas, USA.
Sungyong Won
Shinji Makino
The University of Texas Medical Branch at Galveston · US

Funding

Analysis of Coronavirus-Host Cell InteractionsR01AI099107 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MAKINO, SHINJI · 2012 to 2016
$2.0M
Analysis of SARS Coronavirus-Host Cell InteractionsR01AI072493 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MAKINO, SHINJI · 2007 to 2011
$1.5M
NIAID NIH HHS AI72493NIAID NIH HHS AI99107NIAID NIH HHS R01 AI072493NIAID NIH HHS R01 AI099107
6 · The paper itself

Abstract

The NSm nonstructural protein of Rift Valley fever virus (family Bunyaviridae, genus Phlebovirus) has an antiapoptotic function and affects viral pathogenesis. We found that NSm integrates into the mitochondrial outer membrane and that the protein's N terminus is exposed to the cytoplasm. The C-terminal region of NSm, which contains a basic amino acid cluster and a putative transmembrane domain, targeted the protein to the mitochondrial outer membrane and exerted antiapoptotic function.

Indexed as

Protein TransportAnimalsApoptosis Regulatory ProteinsCell LineHost-Pathogen InteractionsHumansMitochondrial MembranesRift Valley fever virusViral Nonstructural ProteinsApoptosis Regulatory ProteinsViral Nonstructural Proteins

Identifiers

PMID23097454
PMCPMC3536385
OpenAlexW2132532186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.