ArticleHypertension research : official journal of the Japanese Society of Hypertension2013
Rationale, study design, baseline characteristics and blood pressure at 16 weeks in the HONEST Study.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Differences of blood pressure measured at clinic versus at home in the morning and in the evening in Europe and Asia: A systematic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2022Pooled it
- The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).Hypertension research : official journal of the Japanese Society of Hypertension · 2019Guideline
- Interrelationship Between the Morning-to-Evening Changes in Home Blood Pressure and Pulse Rate.American journal of hypertension · 2025Article
- Recommendations for home blood pressure monitoring in Latin American countries: A Latin American Society of Hypertension position paper.Journal of clinical hypertension (Greenwich, Conn.) · 2020Review
- Increased cardiovascular risk of treated white coat and masked hypertension in patients with diabetes and chronic kidney disease: the HONEST Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Observational
- Home blood pressure and cardiovascular risk in treated hypertensive patients: the prognostic value of the first and second measurements and the difference between them in the HONEST study.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Observational
- Persistent olmesartan-based blood pressure-lowering effects on morning hypertension in Asians: the HONEST study.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Observational
- Differences between clinic blood pressure and morning home blood pressure, as shown by Bland-Altman plots, in a large observational study (HONEST study).Hypertension research : official journal of the Japanese Society of Hypertension · 2015Observational
- Clinical Practice of Two Measurements of Home Blood Pressure on Each Occasion in Patients with Chronic Kidney Disease.Cardiorenal medicine · 2015Article
- Effect of Olmesartan-Based Therapies on Therapeutic Indicators Obtained Through Out-of-Office Blood Pressure.Cardiology and therapy · 2015Article
- Effectiveness of olmesartan-based treatment on home and clinic blood pressure in elderly patients with masked and white coat hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2015Observational
- Effect of olmesartan on blood pressure in patients with hypertension: specification on causality.Journal of human hypertension · 2015Article
- HONEST to clarify association between home blood pressure and cardiovascular events under antihypertensive medication.Journal of human hypertension · 2015Article
- Effects of olmesartan-based treatment on masked, white-coat, poorly controlled, and well-controlled hypertension: HONEST study.Journal of clinical hypertension (Greenwich, Conn.) · 2014Observational
- Difference in the effects of switching from candesartan to olmesartan or telmisartan to olmesartan in hypertensive patients with type 2 diabetes: the COTO study.Drug design, development and therapy · 2014Article
- Effect of the angiotensin II receptor antagonist olmesartan on morning home blood pressure in hypertension: HONEST study at 16 weeks.Journal of human hypertension · 2013Observational
- Enhanced blood pressure-lowering effect of olmesartan in hypertensive patients with chronic kidney disease-associated sympathetic hyperactivity: HONEST study.Journal of clinical hypertension (Greenwich, Conn.) · 2013Article
Corrections and comments
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8 authors.
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Abstract
On the basis of the studies that investigated the relationship between baseline clinic blood pressure (CBP) or home blood pressure (HBP) values and cardiovascular (CV) events, HBP has been reported to have a stronger prognostic ability. However, few studies have compared the prognostic ability of on-treatment CBP and HBP. The relationship between on-treatment HBP, measured twice in the morning and twice at bedtime, and CV events was investigated in over 20 000 patients in the HONEST (Home blood pressure measurement with Olmesartan Naive patients to Establish Standard Target blood pressure) Study, a prospective, 2-year observational study of treatment with an angiotensin receptor blocker, olmesartan (OLM), in OLM-naive hypertensive patients. This report summarizes the study protocol, the baseline characteristics of the patients and CBP and HBP at 16 weeks. A total of 22 373 patients were registered across Japan; baseline data from 22 162 patients were collected. Baseline HBP (mean±s.d.) in the morning (the first measurement) was 151.6±16.4/87.1±11.8 mm Hg and at bedtime was 144.3±16.8/82.8±11.9 mm Hg, whereas CBP was 153.6±19.0/87.1±13.4 mm Hg. At 16 weeks, morning HBP was 135.0±13.7/78.8±9.9 mm Hg and bedtime HBP was 129.7±13.8/74.7±10.1 mm Hg, whereas CBP was 135.6±15.4/77.6±10.9 mm Hg. The follow-up period for each patient ends on 30 September 2012. The HONEST Study is expected to provide evidence showing the relationship between baseline and on-treatment CBP and HBP levels (both first and second measurements) and CV events.
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