ArticleCytotechnology2013
Harvest site influences the growth properties of adipose derived stem cells.
Article in Cytotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Brown adipose tissue secretes OLFM4 to coordinate sensory and sympathetic innervation via Schwann cells.Nature communications · 2025Article
- The effect of host tissue and radiation on fat-graft survival: A comparative experimental study.JPRAS open · 2023Article
- Engineered hydrogels for peripheral nerve repair.Materials today. Bio · 2023Review
- Augmenting Peripheral Nerve Regeneration with Adipose-Derived Stem Cells.Stem cell reviews and reports · 2022Review
- Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human.Stem cell research & therapy · 2021Article
- Comparison of Fat Harvested from Flank and Falciform Regions for Stem Cell Therapy in Dogs.Veterinary sciences · 2021Article
- Proliferation, Differentiation and Immunoregulatory Capacities of Brown and White Adipose-Derived Stem Cells from Young and Aged Mice.International journal of stem cells · 2020Article
- Application of stem cells in peripheral nerve regeneration.Burns & trauma · 2020Review
- Adipose tissue-derived extracellular matrix hydrogels as a release platform for secreted paracrine factors.Journal of tissue engineering and regenerative medicine · 2019Article
- Regeneration of nerve crush injury using adipose-derived stem cells: A multimodal comparison.Muscle & nerve · 2018Article
- Epineural adipose-derived stem cell injection in a sciatic rodent model.Brain and behavior · 2018Article
- The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery.International wound journal · 2017Review
- Stem Cell Transplantation for Peripheral Nerve Regeneration: Current Options and Opportunities.International journal of molecular sciences · 2017Review
- Characterization of adipose tissue macrophages and adipose-derived stem cells in critical wounds.PeerJ · 2017Article
- Effects of Cryopreservation on Canine Multipotent Stromal Cells from Subcutaneous and Infrapatellar Adipose Tissue.Stem cell reviews and reports · 2016Article
- Paclitaxel impairs adipose stem cell proliferation and differentiation.The Journal of surgical research · 2015Article
- The role of adipose-derived stem cells in breast cancer progression and metastasis.Stem cells international · 2015Review
- Adipose derived stem cells and nerve regeneration.Neural regeneration research · 2014Review
- Adipose-derived stem cells from the breast.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The therapeutic potential of adult stem cells may become a relevant option in clinical care in the future. In hand and plastic surgery, cell therapy might be used to enhance nerve regeneration and help surgeons and clinicians to repair debilitating nerve injuries. Adipose-derived stem cells (ASCs) are found in abundant quantities and can be harvested with a low morbidity. In order to define the optimal fat harvest location and detect any potential differences in ASC proliferation properties, we compared biopsies from different anatomical sites (inguinal, flank, pericardiac, omentum, neck) in Sprague-Dawley rats. ASCs were expanded from each biopsy and a proliferation assay using different mitogenic factors, basic fibroblast growth factor (bFGF) and platelet-derived growth factor (PDGF) was performed. Our results show that when compared with the pericardiac region, cells isolated from the inguinal, flank, omental and neck regions grow significantly better in growth medium alone. bFGF significantly enhanced the growth rate of ASCs isolated from all regions except the omentum. PDGF had minimal effect on ASC proliferation rate but increases the growth of ASCs from the neck region. Analysis of all the data suggests that ASCs from the neck region may be the ideal stem cell sources for tissue engineering approaches for the regeneration of nervous tissue.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.