Evidence map›Paper›PMID 23095874›Full record

ReviewHuman vaccines & immunotherapeutics2012

Recombinant allergens: the present and the future.

Marek Jutel, Katarzyna Solarewicz-Madejek, Sylwia Smolinska

Open access · bronzeAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Comparison of Skin Prick Tests (SPT), Intradermal Tests (IDT) andAnimals : an open access journal from MDPI · 2023
    Article
  3. Selected Technical Aspects of Molecular Allergy Diagnostics.Current issues in molecular biology · 2023
    Review
  4. Egg Allergy: Diagnosis and Immunotherapy.International journal of molecular sciences · 2020
    Review
  5. Review
  6. Review
  7. Review
  8. Allergen Immunotherapy: Past, Present, and Future.Allergy, asthma & immunology research · 2016
    Review
  9. Molecular biomarkers for grass pollen immunotherapy.World journal of methodology · 2014
    Review
  10. Allergen-Specific Immunotherapy in Asthma.Current treatment options in allergy · 2014
    Review
  11. Article
  12. Review
  13. Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Society for Pediatric Allergy and Environmental Medicine (GPA), the Medical Association of German Allergologists (AeDA), the Austrian Society for Allergy and Immunology (ÖGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Dermatology (DDG), the German Society of Oto- Rhino-Laryngology, Head and Neck Surgery (DGHNO-KHC), the German Society of Pediatrics and Adolescent Medicine (DGKJ), the Society for Pediatric Pneumology (GPP), the German Respiratory Society (DGP), the German Association of ENT Surgeons (BV-HNO), the Professional Federation of Paediatricians and Youth Doctors (BVKJ), the Federal Association of Pulmonologists (BDP) and the German Dermatologists Association (BVDD).Allergo journal international
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marek JutelDepartment of Clinical Immunology, Wroclaw Medical University, Wroclaw, Poland. marek.jutel@am.wroc.pl
Katarzyna Solarewicz-Madejek
Sylwia Smolinska
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen specific immunotherapy (SIT) is the only known causative treatment of allergic diseases. Recombinant allergen-based vaccination strategies arose from a strong need to both to improve safety and enhance efficacy of SIT. In addition, new vaccines can be effective in allergies including food allergy or atopic dermatitis, which poorly respond to the current treatment with allergen extracts. A number of successful clinical studies with both wild-type and hypoallergenic derivatives of recombinant allergens vaccines have been reported for the last decade. They showed high efficacy and safety profile as well as very strong modulation of T and B cell responses to specific allergens.

Indexed as

AllergensDesensitization, ImmunologicHumansVaccinesAllergensVaccinesallergen-specific immunotherapyallergyhypoallergensrecombinant allergensvaccines

Identifiers

PMID23095874
PMCPMC3660775
OpenAlexW2317017664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.